NCT02810470

Brief Summary

Malnutrition is a major health problem with serious consequences for the quality of life of elderly people: it increases the number of hospitalizations and lengths of stay, worsens functional dependency and increases morbidity and mortality rates There are numerous recommendations and tools to detect or to manage malnutrition and the prescription of Oral Nutritional Supplements (ONS) can be a solution. As the elderly suffer from food monotony, as well as age-related changes, which may or may not be associated with the presence of disease, it is necessary to ensure full ingestion of the prescribed supplements to optimize the benefits provided by these products. To achieve this it is necessary to know the chemosensory characteristics of foods enjoyed by hospitalized elderly people who are malnourished or at risk of malnutrition. The investigators make the hypothesis that by further optimizing taste and energy content of foods, consumption by the elderly and the health benefits would be improved.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
107

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2015

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2015

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

June 14, 2016

Completed
9 days until next milestone

First Posted

Study publicly available on registry

June 23, 2016

Completed
Last Updated

June 23, 2016

Status Verified

May 1, 2015

Enrollment Period

9 months

First QC Date

June 14, 2016

Last Update Submit

June 20, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Acceptability of the different tested Oral Nutrition Supplement with different flavors

    Hedonic scale after testing at day 2

Study Arms (2)

Cream appreciation tests

EXPERIMENTAL
Dietary Supplement: Fortimel Compact ProteinDietary Supplement: Fortimel Cream

Beverages appreciation tests

EXPERIMENTAL
Dietary Supplement: Fortimel Compact ProteinDietary Supplement: Fortimel Cream

Interventions

Fortimel Compact ProteinDIETARY_SUPPLEMENT

Each product will be tested by all patients spread over 2 days. A first half of volunteers will start the testing process with the beverages at day 1 and continue with the creams at day 2. The second half of volunteers will process inversely (day 1 = creams, day 2 = beverages). The test order of flavors will be randomly allocated to the volunteers among the list of all possible combinations.

Beverages appreciation testsCream appreciation tests
Fortimel CreamDIETARY_SUPPLEMENT

Each product will be tested by all patients spread over 2 days. A first half of volunteers will start the testing process with the beverages at day 1 and continue with the creams at day 2. The second half of volunteers will process inversely (day 1 = creams, day 2 = beverages). The test order of flavors will be randomly allocated to the volunteers among the list of all possible combinations.

Beverages appreciation testsCream appreciation tests

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Person who have given their written informed consent
  • Person aged more than 65 years
  • Person cognitively able to participate in tests and to answer questionnaires (Mini Mental Statement Estimation score (MMSE) equal to or greater than 21)
  • Person with an Mini Nutritional Status score (MNA) lower than 23.5/30 for risk of malnutrition or malnourished
  • Person without known unstable cardiac disease
  • Person without high blood pressure

You may not qualify if:

  • Person who are not covered by national health insurance
  • Person suffering from severe illness during the test
  • Person with a life expectancy lower than 6 months or with a cancer
  • Every person with proven anosmia (total loss of olfaction) from birth or due to physical trauma (head trauma) or disease (acute rhinitis)
  • Person with allergy (soya milk) or severe aversion to one of the foods that will be used during the study
  • Person with swallowing disorders
  • Person with a prescribed strict food diet
  • Person with an instable diabetes

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Malnutrition

Condition Hierarchy (Ancestors)

Nutrition DisordersNutritional and Metabolic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 14, 2016

First Posted

June 23, 2016

Study Start

June 1, 2015

Primary Completion

March 1, 2016

Study Completion

March 1, 2016

Last Updated

June 23, 2016

Record last verified: 2015-05