NCT02779907

Brief Summary

This community-based cross-sectional survey will estimate the frequency and risk factors of Chronic Suppurative Otitis Media and Hearing Impairment in Children ages 4-6 years in the Chikwawa District. These data will be useful for service planning, disease prevention efforts and to guide future research in this field.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
270

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2016

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2016

Completed
5 days until next milestone

First Submitted

Initial submission to the registry

May 6, 2016

Completed
17 days until next milestone

First Posted

Study publicly available on registry

May 23, 2016

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2016

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2016

Completed
Last Updated

June 6, 2016

Status Verified

June 1, 2016

Enrollment Period

2 months

First QC Date

May 6, 2016

Last Update Submit

June 3, 2016

Conditions

Keywords

PaediatricMalawi

Outcome Measures

Primary Outcomes (1)

  • Chronic Suppurative Otitis Media

    Chronic Suppurative Otitis Media will be defined as per the the World Health Organisation ear and hearing survey diagnostic criteria. To assign a diagnosis, tympanic membrane images and clinical data for each participant will be reviewed by two ENT surgeons who will assign a diagnosis. Disagreements will be resolved by a third 'tiebreaker'.

    Day1; This is a Cross-Sectional Survey and each participant will be assessed once. Therefore the outcome will be measured at data collection.

Secondary Outcomes (1)

  • Hearing Impairment at more than 25 decibels hearing loss cutoff at 1000Hz, 2000Hz and 4000Hz

    Day 1; This is a Cross-Sectional Survey and each participant will be assessed once. Therefore the outcome will be measured at data collection.

Study Arms (1)

Study Population

Children aged 4-6 years resident in Chikwawa District.

Other: No Intervention

Interventions

No interventions planned for this observational study

Study Population

Eligibility Criteria

Age4 Years - 6 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

Children aged 4-6 years living in the Chikwawa District

You may qualify if:

  • Child aged 4-6 years old
  • Resident in the CAPS study area in the Chikwawa district of southern Malawi

You may not qualify if:

  • Parent/guardian of participant unable to provide informed consent to their child's participation
  • Participant refusal to assent to participation
  • Participant unable to explicitly assent to involvement in the study (e.g. developmental delay, learning difficulties, unwell)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Malawi-Liverpool-Wellcome Trust Clinical Research Program Chikwawa District Hospital Field Research Sute

Iratu, Chikwawa, PB. 01234, Malawi

RECRUITING

MeSH Terms

Conditions

Hearing Loss

Condition Hierarchy (Ancestors)

Hearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Kevin Mortimer, PHD, MBBS

    LSTM

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Luke Hunt, MBBS

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 6, 2016

First Posted

May 23, 2016

Study Start

May 1, 2016

Primary Completion

July 1, 2016

Study Completion

September 1, 2016

Last Updated

June 6, 2016

Record last verified: 2016-06

Data Sharing

IPD Sharing
Will share

Participants will be consented for anonymised data storage for further research up to a period of 5 years following completion of the study. These data will be held on a secure server at LSTM by the principal investigator. Data may be shared with any interested parties following successful ethical review from COMREC and LSTM.

Locations