NCT02770924

Brief Summary

The aim of this study is to evaluate the visual function of patients with bilateral implantation of the IOL trifocal ZEISS AT LISA TRI AND TRI TORIC by means of visual acuity tests with and without optical correction, sensitivity curve contrast, defocus curve and quality questionnaire visual function (VFQ-25).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for phase_4

Timeline
Completed

Started May 2016

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2016

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

May 4, 2016

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 12, 2016

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2017

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 13, 2017

Completed
Last Updated

September 14, 2017

Status Verified

August 1, 2017

Enrollment Period

1.2 years

First QC Date

May 4, 2016

Last Update Submit

September 13, 2017

Conditions

Keywords

cataractphacoemulsificationAT LISA TRI TORICIOL

Outcome Measures

Primary Outcomes (1)

  • Binocular visual acuity for far, intermediate and near distance

    Visual acuity measurements

    Changes from Pre-Op to Month 3

Secondary Outcomes (3)

  • Defocus Curve

    Month 3

  • Contrast Sensitivity

    Changes from Pre-Op and Month 3

  • VFQ-25 Questionnaire

    Changes from Pre-Op and Month 3

Study Arms (2)

AT LISA TRI TORIC

EXPERIMENTAL

All patients will be undergo to phacoemulsification with IOL implantation bilateral

Device: AT LISA TRI TORIC

AT LISA TRI

EXPERIMENTAL

All patients will be undergo to phacoemulsification with IOL implantation bilateral

Device: AT LISA TRI

Interventions

phacoemulsification with IOL implantation

Also known as: ZEISS AT LISA TRI TORIC
AT LISA TRI TORIC

phacoemulsification with IOL implantation

Also known as: ZEISS AT LISA TRI
AT LISA TRI

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients older than 50 years
  • Cataract diagnosis indicating surgery in both eyes
  • Corneal astigmatism to 12D (AT lisa tri toric)
  • Corneal astigmatism less than 0,75D (AT lisa tri)
  • Ability to provide consent and clarification for study participation

You may not qualify if:

  • Significant irregular corneal astigmatism as shown by Corneal topography;
  • Corneal astigmatism up 12D
  • Patients diagnosed with severe visual degenerative disorders (e.g. macular degeneration or other disorder of the retina)
  • Previous corneal surgery;
  • Amblyopia
  • Planning for multiple procedures, including IRL, LASIK, etc. during surgery or during the study
  • Endothelial dystrophy clinically significant cornea (eg, Fuchs dystrophy)
  • Corneal disease activity (eg, herpes simplex, herpes zoster, etc.)
  • Severe diabetic retinopathy
  • Retinal detachment
  • Glaucoma
  • Patients presenting illness or acute conditions or chronic severe that in the opinion of the investigator, would increase the surgical risk or confound the research results
  • Any patient who is taking part in another study involving ocular surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

IPEPO

São Paulo, 04023062, Brazil

Location

Eye Clinic

São Paulo, 04502-000, Brazil

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Study Officials

  • Rubens Belfort, MD, PhD

    IPEPO Instituto Paulista de Estudos e Pesquisas em Oftalmologia

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 4
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

May 4, 2016

First Posted

May 12, 2016

Study Start

May 1, 2016

Primary Completion

July 1, 2017

Study Completion

September 13, 2017

Last Updated

September 14, 2017

Record last verified: 2017-08

Data Sharing

IPD Sharing
Will share

paper publication

Locations