NCT03819582

Brief Summary

Artificial lenses, otherwise known as intraocular lenses (IOLs), are used to replace the natural crystalline lens within the eye during cataract or refractive lens surgery. Monofocal IOLs are the traditional IOL type used during cataract surgery. These monofocal IOLs provide excellent distance vision, however spectacles are required for reading and intermediate distance tasks. Monofocal Intraocular lenses are the mainstay of cataract surgery, but with advancing technologies and a wider selection of lenses available, demand for improved outcomes, improved lens design and ease of surgical implantation have increased. The purpose of this study is to assess the visual performance of the EyeCee One monofocal intraocular lens. In addition an assessment of the ease of insertion by the surgeon will be quantified.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for phase_4

Timeline
Completed

Started Feb 2018

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2018

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

January 22, 2019

Completed
6 days until next milestone

First Posted

Study publicly available on registry

January 28, 2019

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2020

Completed
Last Updated

January 28, 2019

Status Verified

January 1, 2019

Enrollment Period

1.8 years

First QC Date

January 22, 2019

Last Update Submit

January 24, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • Visual acuity early post operative

    Visual acuity measured in LogMAR early post operatively

    1 month post operatively

  • Visual acuity after 3 months post operatively

    Visual acuity measured in LogMAR measured 3 months post operatively

    3 months post operatively

Secondary Outcomes (1)

  • Ease of use to surgeons

    During surgery

Study Arms (1)

Intraocular lens

EXPERIMENTAL

Subjects implanted with the EyeCee One Intraocular lens

Device: EyeCee One intraocular lens

Interventions

Hydrophobic aspheric monofocal intraocular lens

Intraocular lens

Eligibility Criteria

Age45 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Clinically significant Cataract requiring cataract surgery

You may not qualify if:

  • Amblyopia
  • Corneal astigmatism of \>1.00D
  • Dilated pupil size smaller than 5mm
  • Macular pathology
  • Glaucoma
  • Retinal disease
  • Corneal disease
  • Abnormal iris
  • Pupil deformation
  • Any previous corneal or intraocular surgery
  • Any patient who had surgical complications will also be excluded from participation in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

BMI Southend Hospital

Westcliff-on-Sea, Essex, SS0 9AG, United Kingdom

RECRUITING

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Head of School for Research

Study Record Dates

First Submitted

January 22, 2019

First Posted

January 28, 2019

Study Start

February 1, 2018

Primary Completion

December 1, 2019

Study Completion

January 1, 2020

Last Updated

January 28, 2019

Record last verified: 2019-01

Data Sharing

IPD Sharing
Will not share

Locations