NCT02089698

Brief Summary

To compare the efficiency of surgical procedures using 2 phaco tip designs in torsional phacoemulsification using the bevel-down technique.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Sep 2013

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2013

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2013

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2014

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 12, 2014

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 18, 2014

Completed
Last Updated

March 18, 2014

Status Verified

March 1, 2014

Enrollment Period

Same day

First QC Date

March 12, 2014

Last Update Submit

March 15, 2014

Conditions

Keywords

Kelman tipMini-flaredphacoemulsificationcataract

Outcome Measures

Primary Outcomes (1)

  • Early Treatment Diabetic Retinopathy (ETDRS) visual acuities

    90 days

Secondary Outcomes (1)

  • Phaco time used

    1 day, 90 days

Other Outcomes (1)

  • Cumulative dissipated energy (CDE) required

    1 day, 90 days

Study Arms (2)

Reversed tip

ACTIVE COMPARATOR

Reversed Kelman tip

Device: Mini-flared

Mini-flared

EXPERIMENTAL

Mini-flared Kelman tip

Device: Reversed tip

Interventions

Mini-flared Kelman tip

Reversed tip

Reversed Kelman tip

Mini-flared

Eligibility Criteria

Age40 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients older than 40 years with age-related cataract, and a normal ophthalmologic examination besides senile cataract.

You may not qualify if:

  • Previous ocular surgery, central endothelial cell count less than 2000 cells/mm2, glaucoma or intraocular pressure greater than 21 mmHg, amblyopia, retinal abnormalities, steroid or immunosuppressive treatment, connective tissue diseases, or an allergy or hypersensitivity to NSAIDs. Enrolled patients who had complicated cataract surgery (eg, posterior capsule rupture, vitreous loss, or an intraocular lens not placed in the capsular bag) were subsequently excluded

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Oftalmologico de Brasília

Brasília, Federal District, 70000, Brazil

Location

Related Publications (3)

  • Vargas LG, Holzer MP, Solomon KD, Sandoval HP, Auffarth GU, Apple DJ. Endothelial cell integrity after phacoemulsification with 2 different handpieces. J Cataract Refract Surg. 2004 Feb;30(2):478-82. doi: 10.1016/S0886-3350(03)00620-5.

  • Payne M, Georgescu D, Waite AN, Olson RJ. Phacoemulsification tip vacuum pressure: Comparison of 4 devices. J Cataract Refract Surg. 2006 Aug;32(8):1374-7. doi: 10.1016/j.jcrs.2006.02.066.

  • Frohn A, Dick HB, Fritzen CP. Corneal impact of ultrasound and bevel position in phacoemulsification. J Cataract Refract Surg. 2002 Sep;28(9):1667-70. doi: 10.1016/s0886-3350(02)01306-8.

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Study Officials

  • Patrick F Tzelikis, MD, PhD

    Hospital Oftalmologico de Brasilia

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 12, 2014

First Posted

March 18, 2014

Study Start

September 1, 2013

Primary Completion

September 1, 2013

Study Completion

February 1, 2014

Last Updated

March 18, 2014

Record last verified: 2014-03

Locations