Early Detection of Lung Cancer With Low-dose Multislice Computed Tomography

NCT02754388 | Completed

• 1 other identifier: 201512060RIND
• Study Type: observational
• Target: 1,334
• Locations: 0 countries
• Sites: N/A

Brief Summary

Lung cancer is one of the leading causes of cancer-related death in Taiwan. Early diagnosis of lung cancer may improve cancer survival. Low-dose computed tomography (LDCT) was thought to be the best screening tool for lung cancer. However, there is growing concerns about radiation exposure, high cost, and high rate of false-positive screening result. Epidemiologic studies from western countries showed that cigarette smoking is the major cause of lung cancer, and other risk factors may include age, environmental pollution, occupational exposures (included of radon exposure), gender, race, and pre-existing lung diseases. Adenocarcinoma is the major type of lung cancer in Taiwan and is less attributable to smoking. The investigators need a different risk prediction model adapted to the investigators country. National Taiwan University Hospital Chu-Tung Branch initiated the lung cancer screening by LDCT since June 2015. Many people can get the LDCT screening with affordable price with the subsidy from enterprise donation. The purpose of this study is observing those participants with 2-year follow-up. Furthermore, those data may connect with another study of "Low dose computed tomography screening study in nonsmoker with risk factors for lung cancer in Taiwan" （Non-smoker study）which is implemented in other hospitals in Taiwan.For reality limiting, After one year, the enrollment rate was a lot lower than expected. We extended the enrollment time but only observe those participants for one year not two year..

Conditions

Lung Cancer

Keywords

LDCT, screening, health behavior, psychological factors

Outcome Measures

Primary Outcomes (1)

• Abnormal ct finding detection rate

  Abnormal ct finding detection rate is defined as number of abnormal ct finding/total enroll number

  1-month

Secondary Outcomes (2)

• Change in Chinese 14-item Perceived Stress Scale (Chinese 14-item PSS) score

  6-month

• Change in Chinese Health Questionnaire-12 (CHQ-12) score

  12-month

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients received LDCT screening at NTUH Chu-Tung Branch

You may qualify if:

• age\>=20
• self pay the LDCT in National Taiwan University Hospital Chu-Tung Branch
• ability to understand the informed consent form for complete the questionnaires
• be willing and able to accept telephone access at the time scheduled

Sponsors & Collaborators

• National Taiwan University Hospital: lead

MeSH Terms

Conditions

Lung Neoplasms; Health Behavior

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases; Behavior

Study Officials

• Ding-Cheng Chan, MD, PhD

  National Taiwan University Hospital Chu-Tung Branch

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: OTHER
• Target Duration: 52 Weeks
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 10, 2016
• First Posted: April 28, 2016
• Study Start: February 1, 2016
• Primary Completion: May 1, 2017
• Study Completion: December 1, 2019
• Last Updated: February 28, 2020

Record last verified: 2020-02

Data Sharing

• IPD Sharing: Will not share