Iraqi Trial for Lung Cancer Screening
ITLUCAS
1 other identifier
interventional
500
1 country
1
Brief Summary
Lung cancer is a global problem. Worldwide, 1.2 million people die of lung cancer each year. In Iraq, lung cancer is the most common malignancy after breast cancer and the leading cause of cancer-related death. Tobacco smoking plays a major role in lung cancer; it is reported in 85-90% of lung cancer patients yet environmental tobacco smoke, environmental and domestic air pollution, work-related risk factors, radon exposure, and viruses may also have an impact on lung cancer incidence rates. Early detection of the disease before patients develop symptoms considers the best way to improve patient outcomes. IT LUCAS is designed to evaluate the utility of low-dose computed tomography (LDCT) screening in early detection and management of lung cancer in high-risk people.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable lung-cancer
Started Jun 2018
Typical duration for not_applicable lung-cancer
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2018
CompletedFirst Submitted
Initial submission to the registry
April 22, 2020
CompletedFirst Posted
Study publicly available on registry
April 29, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2022
CompletedMarch 8, 2021
March 1, 2021
3.5 years
April 22, 2020
March 4, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
The efficacy of LD CT in lung cancer screening
The number of lung nodules with Lung RADS 4A, 4B and 4X, cancer predictive value and false-positive value
2 years
Secondary Outcomes (1)
noncancerous lung lesions
2 years
Study Arms (1)
screening
EXPERIMENTALParticipants undergo low dose CT of the chest
Interventions
Invited participants from institutes exposed to a high level of smoke pollution such as employees of Transport and Oil Ministries are inquired for their personal history of cigarette smoking then subjected to low dose CT
Eligibility Criteria
You may qualify if:
- male or female
- aged between 50 and 75
- smokers or ex-smoker
- tobacco exposure of more than 30 pack-years
You may not qualify if:
- History of cancer within the last 5 years other than non-melanoma skin cancer or carcinoma in situ,
- heart or respiratory severe co-morbidity with contraindications to thoracoscopy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Oncology Teaching Hospital
Baghdad, Iraq
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Enam A Khalil
Oncology Teaching Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- SCREENING
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 22, 2020
First Posted
April 29, 2020
Study Start
June 1, 2018
Primary Completion
December 1, 2021
Study Completion
April 1, 2022
Last Updated
March 8, 2021
Record last verified: 2021-03
Data Sharing
- IPD Sharing
- Will not share