NCT02751164

Brief Summary

A retrospective analysis of the Case Mix Programme database to evaluate the association between day and time of admission to critical care and acute hospital outcome for unplanned admissions to adult, general critical care units in England, Wales and Northern Ireland.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
195,428

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2013

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2013

Completed
3.1 years until next milestone

First Submitted

Initial submission to the registry

April 19, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 26, 2016

Completed
5 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2016

Completed
Last Updated

September 7, 2016

Status Verified

September 1, 2016

Enrollment Period

3.1 years

First QC Date

April 19, 2016

Last Update Submit

September 5, 2016

Conditions

Critical Illness

Outcome Measures

Primary Outcomes (1)

  • Acute hospital mortality

    Death before ultimate discharge from acute hospital

    Discharge from acute hospital, an average of 22 days

Study Arms (4)

Weekday daytime

Admitted to the critical care unit Monday-Friday 08:00-17:59

Other: Day/time of admission to the critical care unit

Weekend daytime

Admitted to the critical care unit Saturday-Sunday 08:00-17:59

Other: Day/time of admission to the critical care unit

Weekday night

Admitted to the critical care unit Monday-Friday 18:00-07:59 the next day

Other: Day/time of admission to the critical care unit

Weekend night

Admitted to the critical care unit Saturday-Sunday 18:00-07:59 the next day

Other: Day/time of admission to the critical care unit

Interventions

Day/time of admission to the critical care unitOTHER
Weekday daytimeWeekday nightWeekend daytimeWeekend night

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Unplanned admissions to National Health Service adult, general critical care units in England, Wales and Northern Ireland

You may qualify if:

  • Adult patients (age 16 years or older)
  • Unplanned admission to the critical care unit (i.e. excluding admissions from theatre following elective or scheduled surgery, planned local medical admissions, planned transfers and repatriations)

You may not qualify if:

  • Readmission of the same patient to the critical care unit during the same acute hospital stay
  • Transfer from another critical care unit
  • Transfer from another acute hospital
  • Admission for organ donation
  • Missing time of admission
  • Missing acute hospital outcome
  • Missing key confounders (age, location prior to admission, primary reason for admission, all physiology)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Critical Illness

Condition Hierarchy (Ancestors)

Disease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • David Harrison

    Intensive Care National Audit & Research Centre

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Senior Statistician

Study Record Dates

First Submitted

April 19, 2016

First Posted

April 26, 2016

Study Start

April 1, 2013

Primary Completion

May 1, 2016

Study Completion

May 1, 2016

Last Updated

September 7, 2016

Record last verified: 2016-09

Data Sharing

IPD Sharing
Will not share