Cost Effectiveness Analysis of Critical Care in Resource Limited Setting

NCT02556476 | Completed

• 1 other identifier: CCUS-2435/11
• Study Type: observational
• Target: 148
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study was to examine the cost effectiveness of critical care in a middle income country with limited resources. The main study hypothesis was that critical care is cost effective in low resources setting.

Conditions

Critical Illness

Keywords

critical care; intensive care; health related quality of life; cost benefit analysis

Outcome Measures

Primary Outcomes (1)

• survival

  mortality was recorded one year after hospital discharge and subtracted from the value od 100% in order to get one year survival

  one year after hospital release

Secondary Outcomes (2)

• mortality

  30 days and 60 days after critical illness onset and one year after hospital release

• health related quality of life (HRQOL)

  one year after hospital release

Study Arms (1)

ICU patients

The actual cohort of 148 critically ill medical patients that received the treatment in the intensive care unit (ICU). The interventions include interventions that are usually performed within the ICU such as mechanical ventilation, non-invasive ventilation, neuromuscular blockade, renal replacement therapy.

Procedure: mechanical ventilation; Procedure: neuromuscular blockade; Procedure: renal replacement therapy; Procedure: non-invasive ventilation

Interventions

mechanical ventilation PROCEDURE

ventilator support for the patients presenting with acute respiratory failure

Also known as: ventilator

ICU patients

neuromuscular blockade PROCEDURE

paralysis of the skeletal muscles in order to optimize mechanical ventilation, especially during ARDS

Also known as: neuromuscular block

ICU patients

renal replacement therapy PROCEDURE

the procedures used to treat acute kidney injury

Also known as: continuous hemofiltration (CHF) or hemodiafiltration (CHDF)

ICU patients

non-invasive ventilation PROCEDURE

Procedure used for ventilation support in patients with congestive heart failure, pulmonary edema, COPD and some other conditions.

Also known as: continuous positive airway pressure (CPAP)

ICU patients

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

consecutive critically ill patients treated during one year in a recently established medical ICU at the Sarajevo University Clinical Center.

You may qualify if:

• patients treated between June 1 2011 and June 29 2012 in the medical ICU

You may not qualify if:

• Patients who stayed in the ICU less than 24 hours and
• hospital readmissions

Sponsors & Collaborators

• University of Sarajevo: lead

MeSH Terms

Conditions

Critical Illness

Interventions

Respiration, Artificial; Ventilators, Mechanical; Neuromuscular Blockade; Renal Replacement Therapy; Hemodiafiltration; Noninvasive Ventilation; Continuous Positive Airway Pressure

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Airway Management; Therapeutics; Resuscitation; Emergency Treatment; Respiratory Therapy; Equipment and Supplies; Anesthesia and Analgesia; Investigative Techniques; Renal Dialysis; Sorption Detoxification; Hemofiltration; Extracorporeal Circulation; Surgical Procedures, Operative; Positive-Pressure Respiration

Study Officials

• Hajrunisa Cubro, MD

  Medical ICU University of Sarajevo Clinical Center, Sarajevo, Bosnia and Herzegovina

  PRINCIPAL INVESTIGATOR

• Ognjen Gajic, MD, MSc

  Division of Pulmonary and Critical Care Mayo Clinic Rochester MN USA

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: September 18, 2015
• First Posted: September 22, 2015
• Study Start: June 1, 2011
• Primary Completion: June 1, 2012
• Study Completion: June 1, 2013
• Last Updated: September 22, 2015

Record last verified: 2015-09