NCT03318965

Brief Summary

The objective of the present study was to compare the ability of acute physiology and chronic health evaluation (APACHE) scoring systems with the combination of an anthropometric variable score "adductor pollicis muscle (APM) thickness" to the APACHE systems in predicting mortality in the ICU. Three hundred and four patients enrolled in this prospective observational study. The APM thickness in dominant hand and APACHE II and III scores were measured for each patient upon admission. Given scores for the APM thickness, were added to APACHE score systems to make two composite scores of APACHE II- APM and APACHE III- APM. The accuracy of the two composite models and APACHE II and III systems in predicting mortality of patients was compared using area under the ROC curve. Based on the study results, the area under the ROC curves improved in composite models. Therefore, it seemed that considering anthropometric variables may improve prediction of mortality in APACHE systems.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
304

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2014

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2014

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2016

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

October 10, 2017

Completed
14 days until next milestone

First Posted

Study publicly available on registry

October 24, 2017

Completed
Last Updated

October 24, 2017

Status Verified

October 1, 2017

Enrollment Period

2.4 years

First QC Date

October 10, 2017

Last Update Submit

October 20, 2017

Conditions

Critical Illness

Keywords

MortalityAnthropometryNutrition AssessmentCaliper

Outcome Measures

Primary Outcomes (1)

  • Prediction of Mortality

    Mortality prediction by APACHE -APM

    First day of ICU admission

Eligibility Criteria

Age16 Years+
Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

304 eligible critically ill patients

You may qualify if:

  • Older than 16 years of age

You may not qualify if:

  • Splints, in the upper extremities
  • Casts in the upper extremities
  • Edema in the upper extremities
  • Patients with readmission during the study period
  • Those transferred from other ICUs

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Critical Illness

Condition Hierarchy (Ancestors)

Disease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Zahra Vahdat Shariatpanahi, MD, PhD

    Shahid Beheshti University

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 10, 2017

First Posted

October 24, 2017

Study Start

June 1, 2014

Primary Completion

November 1, 2016

Study Completion

November 1, 2016

Last Updated

October 24, 2017

Record last verified: 2017-10