NCT02750787

Brief Summary

The study is designed to observe the use of a peptide-based oral nutrition supplement in adults with chronic malabsorption or maldigestion who require supplemental nutrition as assessed by a clinician.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
37

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2016

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 19, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 26, 2016

Completed
3 months until next milestone

Study Start

First participant enrolled

August 1, 2016

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2017

Completed
Last Updated

July 24, 2017

Status Verified

July 1, 2017

Enrollment Period

11 months

First QC Date

April 19, 2016

Last Update Submit

July 21, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Study Product Consumption

    Subject Diary

    Day 1 to Day 23

Secondary Outcomes (3)

  • Body Mass Index

    Change from Screening to Day 23

  • Medication Use

    Screening to Study Day 23

  • Adverse Events

    Screening to Day 25

Study Arms (1)

Nutritional Study Product

EXPERIMENTAL

A ready-to-drink peptide-based liquid formula for patients with impaired gastro-intestinal function.

Other: Nutritional Study Product

Interventions

Two 220 ml servings per day

Nutritional Study Product

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject is ≥ 18 years of age.
  • Subject has chronic malabsorption or maldigestion.
  • Subject requires supplemental nutrition as assessed by a clinician.
  • Subject agrees to consume 2 servings of the study product a day for at least 16 consecutive days during Treatment period.

You may not qualify if:

  • Subject is currently taking or has taken antibiotics within 2 weeks prior to enrollment in the study.
  • Subject has current active malignant disease or was treated within the last 6 months for cancer.
  • Subject has a history of diabetes mellitus.
  • Subject is pregnant as demonstrated by a urine pregnancy test.
  • Subject has severe auto immune disease and is on immuno-modulating therapy.
  • Subject has a history of allergy to any of the ingredients in the study product.
  • Subject has active HIV.
  • Subject has a known aversion to flavor of product being tested.
  • Subject has known dementia, brain metastases, eating disorders, history of significant neurological or psychiatric disorder, or any other psychological condition that may interfere with study product consumption.
  • Subject has an obstruction of the gastrointestinal tract precluding ingestion or absorption of the study product.
  • Subject is taking part in another non-Sponsor approved clinical trial.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

St. Boniface Hospital

Winnipeg, Manitoba, R2H 2A6, Canada

Location

MeSH Terms

Conditions

Malabsorption Syndromes

Condition Hierarchy (Ancestors)

Intestinal DiseasesGastrointestinal DiseasesDigestive System DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Officials

  • Jeffrey L Nelson, PhD

    Abbott Nutrition

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 19, 2016

First Posted

April 26, 2016

Study Start

August 1, 2016

Primary Completion

July 1, 2017

Study Completion

July 1, 2017

Last Updated

July 24, 2017

Record last verified: 2017-07

Locations