NCT02736357|WithdrawnDMC
Study Stopped
Study restructured with Central IRB (NCT04996706); accruals reported there.
The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study
LEO
Loading search results
Sponsor study identifier
observational
0
1 country
8
Study Start
July 1, 2015
Actual (reported)Primary Completion
April 17, 2023
Actual (reported)Study Completion
April 17, 2023
Actual (reported)The goal of this infrastructure grant is to establish and maintain a cohort of over 12,000 non-Hodgkin lymphoma (NHL) patients to support broad and cutting-edge research that identifies clinical (including co-morbid diseases), epidemiologic (including lifestyle and other exposures), host genetic, tumor, and treatment factors, as well as the interaction among these factors, on short and long-term outcomes. These efforts will identify new approaches to improve the survival and well-being of NHL patients.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 17, 2023
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 1, 2015
Actual (reported)April 4, 2016
Actual (reported)April 13, 2016
Actual (reported)April 17, 2023
Actual (reported)April 17, 2023
Actual (reported)Overall Survival (OS)
Time from date of diagnosis to date of death
Short (<5 years), medium (5-10 years), and long-term (>10 years)
Event Free Survival (EFS)
Short (<5 years), medium (5-10 years), and long-term (>10 years)
Lymphoma Specific Survival (LSS)
Short (<5 years), medium (5-10 years), and long-term (>10 years)
Newly diagnosed non-Hodgkin Lymphoma willing to provide a research blood sample, return enrollment and follow-up questionnaires, and allow access to medical records.
University of Miami
Miami, Florida, 33136, United States
Emory University
Atlanta, Georgia, 30322, United States
University of Iowa
Iowa City, Iowa, 52242, United States
Mayo Clinic
Rochester, Minnesota, 55902, United States
Washington University
St Louis, Missouri, 63130, United States
Weill Cornell Medical College
New York, New York, 10021, United States
University of Rochester
Rochester, New York, 14642, United States
Ruan J, Chen Z, Larson MC, Bennani NN, Allen P, Mou E, Wallace D, Mehta-Shah N, Lossos IS, Malpica Castillo LE, Jaye DL, Vega F, Inghirami G, Pongas G, Akkad N, Casulo C, Martin P, Cohen JB, Habermann TM, Maurer MJ, Leonard JP, Friedberg JW, Kahl B, Cerhan JR, Flowers CR, Feldman AL. Patterns of care and clinical outcomes in systemic peripheral T-cell lymphoma: the LEO-MER prospective cohort study. Blood Adv. 2026 May 26;10(10):3480-3493. doi: 10.1182/bloodadvances.2025018455.
Research blood draw collected at baseline. Research blood processed and stored as plasma, serum and germline DNA. Tissue in excess of diagnosis stored in formalin fixed paraffin embedded (FFPE) cored for use in Tissue Micro Array (TMA) and extraction of DNA and RNA from tumor.
James Cerhan, MD, PhD
Mayo Clinic
Christopher Flowers, MD
Emory University
0 participants (actual enrollment reported by the registry).
First Submitted
April 4, 2016
First Posted
April 13, 2016
Study Start
July 1, 2015
Actual (reported)An Extension Study of ABT-199 in Subjects With Advanced Non-Hodgkin's Lymphoma
Contact the study team to confirm eligibility.
MD Anderson Cancer Center
Houston, Texas, 77030, United States
Primary Completion
April 17, 2023
Actual (reported)Study Completion
April 17, 2023
Actual (reported)Last Updated
June 22, 2023
Record last verified: 2023-06
There is no plan to make individual participant data (IPD) available.
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: