Effect of Frequent Interruptions of Prolonged Sitting on Self-perceived Levels of Energy, Mood, Food Cravings and Cognitive Function

NCT02717377 | Completed

• 1 other identifier: 13-2777
• Study Type: interventional
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study is designed to test the effects of six 5 minute microbursts of physical activity spread across the day as compared to either a sedentary control condition or a single 30 minute bout of moderate intensity physical activity on cognitive function, self-reported energy levels, aspects of eating behavior and measures of metabolic health. The primary hypotheses are:

1. 1.Hourly 5 minute bouts of moderate intensity exercise during the day will increase afternoon cognitive function as compared to a no exercise condition.
2. 2.Hourly 5 minute bouts of moderate intensity exercise during the day will increase afternoon cognitive function more than a single 30 minute AM bout.
3. 3.Hourly 5 minute bouts of moderate intensity exercise during the day will increase self-reported energy levels, reduce orexigenic appetitive measures and improve measures of metabolic health as compared to a no exercise condition.
4. 4.Hourly 5 minute bouts of moderate intensity exercise during the day will increase self-reported energy levels, reduce orexigenic appetitive measures and improve measures of metabolic health more than a single 30 minute AM bout.

Conditions

Mood; Energy; Food Cravings; Cognitive Function

Keywords

Micro bouts; Physical Activity

Outcome Measures

Primary Outcomes (3)

• Change in Energy and Mood level

  Self-perceived energy and mood were measured by using visual analogue scales (VAS) as described below at baseline.

  During each of the three separate study days energy and mood levels are assessed at (in minutes): T0, T40, T70, T80, T90, T120, T140, T230, T350, T390, T400, T405, T410, and T435

• Change in Cognitive function

  The flanker task is used to measure cognitive function

  During each of the three separate study days cognitive function is measured at (in minutes): T410

• Change in Cognitive Function

  After the Flanker task, the Comprehensive Trail Making Test is used to measure cognitive function during each study day.

  During each of the three separate study days cognitive function is measured at (in minutes): T425

Study Arms (3)

Uninterrupted sitting

NO INTERVENTION

Subjects remained seated all day except to rise from the chair to void.

Sitting + one bout of activity

ACTIVE COMPARATOR

Subjects remained seated all day, except to rise from the chair to void, and to perform one bout of 30-minutes moderate-intensity walking. Physical activity was performed at 0800, after measures of vitals and basal questionnaire assessments, but before breakfast.

Behavioral: physical activity

Sitting + microbursts of activity

EXPERIMENTAL

Subjects rose from the seated position every hour for 6-hours from 0910 to 1430 to complete 5-minute bouts of moderate-intensity walking, yielding a total activity time of 30-minutes.

Behavioral: physical activity

Interventions

physical activity BEHAVIORAL

Sitting + microbursts of activity; Sitting + one bout of activity

Eligibility Criteria

• Age: 19 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• All ethnic groups and both genders
• Age: Lower age limit: 19 years; Upper age limit: 45 years
• Body-mass Index: Lower BMI limit: 18.5 kg/m2; Upper BMI limit: 29.9 kg/m2
• Willing to adhere to caffeine restrictions of no more than two 16 ounce beverages in the morning of each study day with no caffeine intake after 12:00pm on any of the three study days

You may not qualify if:

• History of cardiovascular disease, including coronary artery disease, congestive heart failure, \& unstable angina, or uncontrolled hypertension (\>140/90 mm Hg)
• Currently smoking or stopped smoking in the last 6 months
• Medications affecting weight, energy intake, or energy expenditure in the last 6 months
• Use of oral steroids
• History of stroke or seizures, thyroid disease, type 1 or 2 diabetes, Cushing's syndrome, cerebrovascular, renal disease, hepatic disease, arrhythmias
• Cancer requiring treatment in the past 5 years, with the exception of skin cancers other than melanoma
• Infectious diseases: Self-reported HIV positivity or active tuberculosis
• Inability to exercise for more than 30 minutes on a treadmill at moderate intensity
• Currently pregnant, lactating or less than 6 months post-partum
• History of a major psychiatric disorder including schizophrenia, bipolar illness or psychotic depression
• Score of \>25 on Beck Depression Inventory
• No recreational drug use including marijuana in the past 1 year

Sponsors & Collaborators

• University of Colorado, Denver: lead

Related Publications (1)

• Bergouignan A, Legget KT, De Jong N, Kealey E, Nikolovski J, Groppel JL, Jordan C, O'Day R, Hill JO, Bessesen DH. Effect of frequent interruptions of prolonged sitting on self-perceived levels of energy, mood, food cravings and cognitive function. Int J Behav Nutr Phys Act. 2016 Nov 3;13(1):113. doi: 10.1186/s12966-016-0437-z.

  PMID: 27809874 DERIVED

MeSH Terms

Conditions

Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• James Hill

  University of Colorado, Denver

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 22, 2016
• First Posted: March 23, 2016
• Study Start: November 1, 2013
• Primary Completion: May 1, 2014
• Study Completion: May 1, 2014
• Last Updated: March 23, 2016

Record last verified: 2016-03

Data Sharing

• IPD Sharing: Will not share