NCT02715180

Brief Summary

The almost evidences of the optimal hand position during compression had been based on chest computed tomography (CT) or chest plain films of patients for investigating the effective location for compressing the left ventricle of the heart during cardiopulmonary resuscitation (CPR). However every study was conducted at full inspired state of respiration. A prospective cohort study to evaluate the proper hand position during CPR based on expired respiratory state CT as the health screening would be needed.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
127

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2015

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2015

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

March 14, 2016

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 22, 2016

Completed
Last Updated

April 18, 2018

Status Verified

April 1, 2018

Enrollment Period

4 months

First QC Date

March 14, 2016

Last Update Submit

April 16, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • proper hand position during CPR using the scout film of low dose chest computed tomography

    proper hand position during CPR based on comparison between expiration with the arms at down position and inspiration the arms at raised position. Measurement will be assessed with a length of xiphoid process to arbitrary center of heart

    five months

Secondary Outcomes (1)

  • predicted compressed organs in CPR using the scout film of low dose chest computed tomography Measurement will be assessed with scout film silhouette of organs under quarterly divided sternum.

    five months

Study Arms (1)

Chest computed tomography

OTHER

Low dose chest computed tomography during expiration and inspiration

Radiation: low dose chest computed tomography

Interventions

All participants were evaluated 2 scout films during LDCT screenings. The first scout film was obtained while a participant was holding a comfortable expiration with the arms at down position, and the second scout film was obtained while a full inspiration with the arms at raised position. The axial images of LDCT were taken during participants' full inspiration. The radio-opaque marker was attached to the participants' skin where the lowest part of sternum was palpable, because the sternum moves according to the position of arms and respiration.

Chest computed tomography

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • over 18 years of age
  • no history of heart or lung disease
  • no history of chest or abdominal surgery

You may not qualify if:

  • abnormal findings in LDCT, which might influence inspiration or expiration, were excluded after image interpretation by the board certified radiologists

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (7)

  • Klouche K, Weil MH, Sun S, Tang W, Povoas H, Bisera J. Stroke volumes generated by precordial compression during cardiac resuscitation. Crit Care Med. 2002 Dec;30(12):2626-31. doi: 10.1097/00003246-200212000-00002.

    PMID: 12483049BACKGROUND
  • Perkins GD, Handley AJ, Koster RW, Castren M, Smyth MA, Olasveengen T, Monsieurs KG, Raffay V, Grasner JT, Wenzel V, Ristagno G, Soar J; Adult basic life support and automated external defibrillation section Collaborators. European Resuscitation Council Guidelines for Resuscitation 2015: Section 2. Adult basic life support and automated external defibrillation. Resuscitation. 2015 Oct;95:81-99. doi: 10.1016/j.resuscitation.2015.07.015. Epub 2015 Oct 15. No abstract available.

    PMID: 26477420BACKGROUND
  • Travers AH, Perkins GD, Berg RA, Castren M, Considine J, Escalante R, Gazmuri RJ, Koster RW, Lim SH, Nation KJ, Olasveengen TM, Sakamoto T, Sayre MR, Sierra A, Smyth MA, Stanton D, Vaillancourt C; Basic Life Support Chapter Collaborators. Part 3: Adult Basic Life Support and Automated External Defibrillation: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Circulation. 2015 Oct 20;132(16 Suppl 1):S51-83. doi: 10.1161/CIR.0000000000000272.

    PMID: 26472859BACKGROUND
  • Cha KC, Kim HJ, Shin HJ, Kim H, Lee KH, Hwang SO. Hemodynamic effect of external chest compressions at the lower end of the sternum in cardiac arrest patients. J Emerg Med. 2013 Mar;44(3):691-7. doi: 10.1016/j.jemermed.2012.09.026. Epub 2012 Dec 4.

    PMID: 23218197BACKGROUND
  • Qvigstad E, Kramer-Johansen J, Tomte O, Skalhegg T, Sorensen O, Sunde K, Olasveengen TM. Clinical pilot study of different hand positions during manual chest compressions monitored with capnography. Resuscitation. 2013 Sep;84(9):1203-7. doi: 10.1016/j.resuscitation.2013.03.010. Epub 2013 Mar 15.

    PMID: 23499897BACKGROUND
  • Orlowski JP. Optimum position for external cardiac compression in infants and young children. Ann Emerg Med. 1986 Jun;15(6):667-73. doi: 10.1016/s0196-0644(86)80423-1.

    PMID: 3706857BACKGROUND
  • Pickard A, Darby M, Soar J. Radiological assessment of the adult chest: implications for chest compressions. Resuscitation. 2006 Dec;71(3):387-90. doi: 10.1016/j.resuscitation.2006.04.012. Epub 2006 Sep 18.

    PMID: 16982125BACKGROUND

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

March 14, 2016

First Posted

March 22, 2016

Study Start

August 1, 2015

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

April 18, 2018

Record last verified: 2018-04

Data Sharing

IPD Sharing
Will not share