NCT02711150

Brief Summary

The purpose of this study is to assess whether application of an epidural positioning device to a parturient seated for neuraxial anaesthesia increase the size of the paramedian target area for neuraxial needle insertion. Lumbar ultrasonography will be performed in 30 pregnant women in two seated positions: (P1), lumbar flexion; and (P2), as in P1 with the epidural positioning device applied. For each position, the size of the 'target area', defined as the visible length of the posterior longitudinal ligament will be measured at the L3-L4 interspace.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2016

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 26, 2016

Completed
2 months until next milestone

First Posted

Study publicly available on registry

March 17, 2016

Completed
2 months until next milestone

Study Start

First participant enrolled

May 3, 2016

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 7, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 7, 2016

Completed
Last Updated

March 7, 2018

Status Verified

March 1, 2018

Enrollment Period

5 months

First QC Date

January 26, 2016

Last Update Submit

March 5, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Increase in PLL with the application of an EPD

    12 months

Study Arms (2)

EPD Measurements

EXPERIMENTAL

Intervention: PLL Length Measured through US will be done with the subject placed on the Epidural Positioning Device.

Device: PLL Length Measured through US

Flexed Position Measurements

ACTIVE COMPARATOR

Intervention: PLL Length Measured through US will be done with the subject placed in a "flexed" lumbar spine position.

Device: PLL Length Measured through US

Interventions

The PLL will be measured for each allocated position: EPD or Flexed Position

Also known as: PLL length
EPD MeasurementsFlexed Position Measurements

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Female Patients
  • Term Pregnancy (\>37 weeks)
  • years or older
  • Non-labouring patients, admitted for a cesarean delivery

You may not qualify if:

  • Allergy to ultrasound jelly
  • Spinal Deformities
  • Active Labour
  • Presence of Epidural Catheter for Labour Analgesia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Jones AR, Carle C, Columb M. Effect of table tilt on ligamentum flavum length measured using ultrasonography in pregnant women*. Anaesthesia. 2013 Jan;68(1):27-30. doi: 10.1111/anae.12006. Epub 2012 Oct 22.

    PMID: 23088766BACKGROUND
  • Grau T, Leipold RW, Horter J, Conradi R, Martin EO, Motsch J. Paramedian access to the epidural space: the optimum window for ultrasound imaging. J Clin Anesth. 2001 May;13(3):213-7. doi: 10.1016/s0952-8180(01)00245-8.

    PMID: 11377160BACKGROUND

Study Officials

  • Indu Singh, MD, FRCPC

    Western University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SCREENING
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 26, 2016

First Posted

March 17, 2016

Study Start

May 3, 2016

Primary Completion

October 7, 2016

Study Completion

October 7, 2016

Last Updated

March 7, 2018

Record last verified: 2018-03

Data Sharing

IPD Sharing
Will not share