Functional Outcomes of Stay Strong Stay Healthy Program

NCT02677363 | Completed

• 1 other identifier: 208531
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Strength training can increase muscle mass and strength while improving bone density and reducing risk for osteoporosis and related fractures. Strength training can also lead to reduced risk for diabetes, heart disease, arthritis, depression, and obesity; and improves self-confidence, sleep and vitality. Research demonstrates that strength training is extremely effective in helping aging adults with chronic conditions prevent further onset of disease and, in many instances, actually reverse the disease process. In Stay Strong, Stay Healthy Program elderly subjects perform resistance exercise training (RET) twice every week. Past literature suggests that resistance training improved muscle activity, muscle strength, muscle mass, and bone mineral density and total body composition, and adiponectin, insulin sensitivity, fasting blood-glucose (BG), HbA1c1 (long-term marker of BG), blood pressure (BP), blood triglycerides (TGs) and low density lipoproteins (LDL) in healthy and diabetic subjects. The purpose of this study is to measure the changes in the above discussed variables after 8-weeks of resistance exercises.

Conditions

Quality of Life; Aging; Memory Loss; Cardiovascular Diseases

Keywords

Elderly; Older; Adults; Resistant Exercise; Strength Training; Cognitive function

Outcome Measures

Primary Outcomes (1)

• Muscle electrical activity

  Measurement of muscle electrical activity is made using electromyography technique at baseline and after 8 weeks of resistance exercise.

  Change in muscle electrical activity in 8 weeks in response to resistance exercise program

Secondary Outcomes (3)

• Exert muscle power/strength

  Change in muscle power/strength in 8 weeks in response to resistance exercise program

• Muscle mass loss

  Change in muscle mass in 8 weeks in response to resistance exercise program

• Ability to think or remember

  Changes in thinking and cognitive abilities in 8 weeks in response to resistance exercise program

Study Arms (1)

Older adults

EXPERIMENTAL

Participants 60 and above aged (both females and males) will perform one hour of resistance exercise twice weekly for 8 weeks.

Other: Resistance Exercise

Interventions

Resistance Exercise OTHER

Participants 60 and above aged (both females and males) will perform one hour of resistance exercise twice weekly for 8 weeks.

Also known as: Strength training

Older adults

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 60 or above
• Enrollment in Stay Strong Stay Healthy Program
• Strength training \< 2 hours/week for past 3 months

You may not qualify if:

• Not enrolled in Stay Strong Stay Healthy Program
• Strength training \> 2 hours/week for past 3 months
• Donated more than 463 ml of blood in past 8 weeks
• Physician discouraged to participate

Sponsors & Collaborators

• University of Missouri-Columbia: lead

Study Sites (1)

University of Missouri-Columbia

Columbia, Missouri, 65211, United States

Location

Related Publications (7)

• Geirsdottir OG, Arnarson A, Briem K, Ramel A, Jonsson PV, Thorsdottir I. Effect of 12-week resistance exercise program on body composition, muscle strength, physical function, and glucose metabolism in healthy, insulin-resistant, and diabetic elderly Icelanders. J Gerontol A Biol Sci Med Sci. 2012 Nov;67(11):1259-65. doi: 10.1093/gerona/gls096. Epub 2012 Apr 10.

  PMID: 22496538 BACKGROUND

• Sale DG. Neural adaptation to resistance training. Med Sci Sports Exerc. 1988 Oct;20(5 Suppl):S135-45. doi: 10.1249/00005768-198810001-00009.

  PMID: 3057313 BACKGROUND

• Pollock ML, Franklin BA, Balady GJ, Chaitman BL, Fleg JL, Fletcher B, Limacher M, Pina IL, Stein RA, Williams M, Bazzarre T. AHA Science Advisory. Resistance exercise in individuals with and without cardiovascular disease: benefits, rationale, safety, and prescription: An advisory from the Committee on Exercise, Rehabilitation, and Prevention, Council on Clinical Cardiology, American Heart Association; Position paper endorsed by the American College of Sports Medicine. Circulation. 2000 Feb 22;101(7):828-33. doi: 10.1161/01.cir.101.7.828. No abstract available.

  PMID: 10683360 BACKGROUND

• Mayer F, Scharhag-Rosenberger F, Carlsohn A, Cassel M, Muller S, Scharhag J. The intensity and effects of strength training in the elderly. Dtsch Arztebl Int. 2011 May;108(21):359-64. doi: 10.3238/arztebl.2011.0359. Epub 2011 May 27.

  PMID: 21691559 BACKGROUND

• Kraemer WJ, Ratamess NA. Hormonal responses and adaptations to resistance exercise and training. Sports Med. 2005;35(4):339-61. doi: 10.2165/00007256-200535040-00004.

  PMID: 15831061 BACKGROUND

• Macaluso A, De Vito G. Muscle strength, power and adaptations to resistance training in older people. Eur J Appl Physiol. 2004 Apr;91(4):450-72. doi: 10.1007/s00421-003-0991-3. Epub 2003 Nov 25.

  PMID: 14639481 BACKGROUND

• Ball S, Gammon R, Kelly PJ, Cheng AL, Chertoff K, Kaume L, Abreu EL, Brotto M. Outcomes of Stay Strong, Stay Healthy in community settings. J Aging Health. 2013 Dec;25(8):1388-97. doi: 10.1177/0898264313507318. Epub 2013 Oct 22.

  PMID: 24150062 RESULT

MeSH Terms

Conditions

Memory Disorders; Cardiovascular Diseases

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Stephen D Ball, PhD

  University of Missouri-Columbia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 2, 2016
• First Posted: February 9, 2016
• Study Start: February 1, 2016
• Primary Completion: June 1, 2017
• Study Completion: June 1, 2017
• Last Updated: April 3, 2018

Record last verified: 2018-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)