OCEAN Registry: Obesity and Clock for Elegant Aging Registry
OCEAN
1 other identifier
observational
2,000
1 country
1
Brief Summary
This study aims to study the relationships between obesity, circadian rhythm, and aging. The investigators set up a prospective cohort registry for morbid obesity, obesity, and normal subjects with annual follow-up. The cohort aims to investigate the pathophysiological, molecular, genetic, and cellular aspects of the relationships between obesity, circadian deregulation, and impacts on aging. Clinical data, questionnaires, biological material, and molecular signatures will be collected and investigated.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jul 2011
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2011
CompletedFirst Submitted
Initial submission to the registry
January 26, 2016
CompletedFirst Posted
Study publicly available on registry
February 4, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 1, 2026
February 28, 2024
February 1, 2024
14.9 years
January 26, 2016
February 27, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Body weight
10 years
Secondary Outcomes (3)
Major Cardiovascular Adverse Events
3, 6, 12, and 18 months. 2, 5, and 10 years
Sleep quality as assessed by Pittsburgh Sleep Quality Index (PSQI) questionnaire
3, 6, 12, and 18 months. 2, 5, and 10 years
Personal chronotype (biological clock) as assessed by Munich Chronotype Questionnaire
3, 6, 12, and 18 months. 2, 5, and 10 years
Study Arms (3)
Extreme obesity
BMI ≥35kg/m2
Obesity
BMI 24-34.9kg/m2
Normal subjects
BMI \<24kg/m2. No systemic disease, including hypertension, diabetes, liver cirrhosis, chronic kidney disease, and psychiatric disease.
Eligibility Criteria
Subjects will be recruited from the general population including healthcare facility and non-health care settings. Healthcare facility includes university based hospital and primary care clinics. Non-health care settings include schools, subjects families, and employment agencies.
You may qualify if:
- Age ≥ 20 years old
- Body mass index ≥ 24 kg/m2
- For normal subjects, Body mass index \< 24 kg/m2
You may not qualify if:
- No inform consent
- Use of steroid medications
- Severe systemic diseases or organ failure with estimated life expectancy of 6 months or less
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Chang Gung Memorial Hospital
Taoyuan District, 333, Taiwan
Biospecimen
A. Serum. B. White blood cells. C. Adipose tissue. (If receiving liposuction, plastic surgery, bariatric surgery, dermatological procedure, intra-abdominal operation, and cardiovascular surgery)
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Chao-Yung Wang, MD
Chang Gung Memorial Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 10 Years
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Doctor
Study Record Dates
First Submitted
January 26, 2016
First Posted
February 4, 2016
Study Start
July 1, 2011
Primary Completion (Estimated)
June 1, 2026
Study Completion (Estimated)
June 1, 2026
Last Updated
February 28, 2024
Record last verified: 2024-02