A Cohort Research of Genetic Susceptibility for Common Obesity in Women
CROWN
CROWN
Sponsor study identifier
observational
1,200
1 country
1
Study Start
September 2011
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
July 2014
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 2014
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Not many studies examined genetic determinants of obesity in women. As pre-menopausal and post-menopausal women appear to have different propensities for fat deposition, genetic loci linked with obesity-related phenotypes might be different by menopausal status. So far, there is no large scale of genetic study deciphering common obesity focusing on women population to examine the contributions of aging and change in menopausal status to obesity in Taiwan. The investigators propose this study to compare phenotypic profiles of obesity and cardio-metabolic factors in pre-menopausal and post-menopausal women. The study will examine the contributions of aging and change in menopausal status to the changes of obesity-related traits during the transition from pre-menopause to post-menopause period, and will evaluate the contribution of genetic susceptibility on body fat deposition among women at different stage of menopause.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2014
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 2011
Date type not reportedThis date has not been verified as actual or estimated.
December 6, 2011
Actual (reported)December 8, 2011
Actual (reported)July 2014
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
December 2014
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
genetic associations with body-mass index and waist circumference.
genetic associations with body-mass index and waist circumference.
3 years
genetic associations with body fat composition
3 years
genetic associations with the metabolic syndrome
3 years
600 health premenopausal Women
600 healthy postmenopausal women
The design of the project is a hospital-based case-control study. We will recruit two study groups: 600 post-menopausal women; 600 premenopausal women.
Taipei Veterans General Hospital
Taipei, 112, Taiwan
DNA, fasting blood samples
Chii-Min Hwu, MD
Taipei Veterans General Hospital, Taiwan
First Submitted
December 6, 2011
First Posted
December 8, 2011
Study Start
September 2011
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
July 2014
Reducing Menopausal Symptoms for Women During Menopause Using Group Education in a Primary Health Care Setting
Contact the study team to confirm eligibility.
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 2014
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
December 14, 2011
Record last verified: 2011-12
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