NCT02666638

Brief Summary

The objective of this study is to determine whether these new image acquisition strategies and techniques using of up to 7T can produce meaningful structural and physiological information that can serve to improve our understanding of various disease processes in the clinical setting. 200 Control volunteers will be scanned for approximately one hour, without contrast, on up to 7T MRI scanner. 200 Study Participants will be scanned using newly developed imaging software or hardware that conforms to applicable FDA standards and recommendations. The data (images) for the Control and Experimental Group will be de-identified by the scan technologist and downloaded to a workstation within the Radiology Department for offline processing. These images will be reviewed by a trained Radiologist after the subject has departed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
69

participants targeted

Target at P50-P75 for not_applicable healthy

Timeline
Completed

Started Sep 2015

Longer than P75 for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 18, 2015

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 21, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 28, 2016

Completed
6.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 24, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 24, 2022

Completed
Last Updated

April 1, 2022

Status Verified

March 1, 2022

Enrollment Period

6.5 years

First QC Date

January 21, 2016

Last Update Submit

March 24, 2022

Conditions

Keywords

Magnetic Resonance Imaging (MRI)

Outcome Measures

Primary Outcomes (6)

  • Change in signal to noise ratio using statistical analysis

    25 minutes

  • Change in spatial resolution using statistical analysis

    25 minutes

  • Change in Temporal Resolution using statistical analysis

    25 minutes

  • Change in Image Contrast using statistical analysis

    25 Minutes

  • Change in image homogeneity using statistical analysis

    25 minutes

  • Change in artifact reduction using statistical analysis

    25 minutes

Study Arms (2)

Control Volunteers

ACTIVE COMPARATOR

MRI on up to a 7T scanner without contrast.

Other: Control Volunteers

Clinical Patients

EXPERIMENTAL

MRI on up to a 7T scanner without contrast.+ 10 minutes of research development imaging added onto their clinical MRI scans.

Other: Clinical Volunteers

Interventions

MRI on up to a 7T scanner without contrast.

Control Volunteers

One-hour MRI on up to a 7T scanner without contrast + 10 minutes of research development imaging using radio frequency (RF) coils

Clinical Patients

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Healthy control volunteers, male and female, ages 18 and older (no history of chronic illness, concussion, malignancies, etc.)

You may not qualify if:

  • Contraindications with MRI (e.g. pacemakers or ferromagnetic material near vital structures, etc.)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New York University School of Medicine

New York, New York, 10016, United States

Location

Study Officials

  • Yongxian Qian, MD

    New York University Medical School

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 21, 2016

First Posted

January 28, 2016

Study Start

September 18, 2015

Primary Completion

March 24, 2022

Study Completion

March 24, 2022

Last Updated

April 1, 2022

Record last verified: 2022-03

Locations