Acute Exacerbation of Chronic Obstructive Pulmonary Disease Inpatient Registry Study
AECOPD-IRS
1 other identifier
observational
7,600
0 countries
N/A
Brief Summary
The purpose of this study is to investigate the demographic characteristics, clinical features, diagnoses and treatments of AECOPD hospitalized patients in China, and disease prognosis and its economic burden.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2016
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2016
CompletedFirst Submitted
Initial submission to the registry
January 14, 2016
CompletedFirst Posted
Study publicly available on registry
January 18, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2020
CompletedFebruary 4, 2016
February 1, 2016
11 months
January 14, 2016
February 3, 2016
Conditions
Outcome Measures
Primary Outcomes (2)
In-hospital mortality
All-cause and cause-specific mortality will be described.
12 months
Readmission
Readmission rate caused by AECOPD within 1 month after discharged from hospital.
12 months
Secondary Outcomes (4)
All-cause and cause-specific mortality
3 years
Recurrence of acute exacerbation of COPD
3 years
Lung function and quality of life assessment
3 years
Healthcare costs
12 months
Eligibility Criteria
AECOPD-IRS plans to enroll 7600 hospitalized patients (≥ 18 years old with main diagnosis as AECOPD). Sample size estimation is based on estimated mortality of AECOPD hospitalized patients (\~5%). Study patients will be recruited from 40-60 hospitals across China,each hospital will recruit 152-190 patients. Hospital selection follows a multi-stage sampling strategy.
You may qualify if:
- ≥18 years of age; hospitalized patients with main diagnosis as AECOPD.
You may not qualify if:
- Patients diagnosed as active pulmonary tuberculosis, or acute left heart failure; Patients participating in clinical trials or intervention studies of drugs.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- China-Japan Friendship Hospitallead
- Peking Universitycollaborator
- China Soong Ching Ling Foundationcollaborator
Related Publications (2)
Niu Y, Niu H, Meng X, Zhu Y, Ren X, He R, Wu H, Yu T, Zhang Y, Kan H, Chen R, Yang T, Wang C. Associations Between Air Pollution and the Onset of Acute Exacerbations of COPD: A Time-Stratified Case-Crossover Study in China. Chest. 2024 Nov;166(5):998-1009. doi: 10.1016/j.chest.2024.05.030. Epub 2024 Jun 19.
PMID: 38906462DERIVEDHe R, Wang Y, Ren X, Huang K, Lei J, Niu H, Li W, Dong F, Li B, Yang T, Wang C. Associations of medication regimen complexity with medication adherence and clinical outcomes in patients with chronic obstructive pulmonary disease: a prospective study. Ther Adv Respir Dis. 2023 Jan-Dec;17:17534666231206249. doi: 10.1177/17534666231206249.
PMID: 37855117DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Target Duration
- 3 Years
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Prof.Dr.
Study Record Dates
First Submitted
January 14, 2016
First Posted
January 18, 2016
Study Start
January 1, 2016
Primary Completion
December 1, 2016
Study Completion
January 1, 2020
Last Updated
February 4, 2016
Record last verified: 2016-02