Staging Procedures to Diagnose Malignant Pleural Mesothelioma

NCT02648763 | Terminated

• 1 other identifier: 15-007647
• Study Type: observational
• Target: 33
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to evaluate the accuracy of participants imaging versus staging procedures. The investigators will consent subjects that are scheduled to undergo staging procedures to diagnose malignant pleural mesothelioma (including pleuroscopy, bronchoscopy, endobronchial ultrasound and laparoscopy) as part of their standard of care.

Conditions

Mesothelioma; Solitary Fibrous Tumor of the Pleura

Outcome Measures

Primary Outcomes (1)

• Accuracy of surgical staging versus imaging procedures based on surgical findings.

  The staging imaging will be compared with the actual surgical staging procedure to evaluate the accuracy of the imaging.

  2 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients receiving treatment at the Mayo Clinic Rochester that are scheduled to undergo staging procedures to diagnose malignant pleural mesothelioma (including pleuroscopy, bronchoscopy, endobronchial ultrasound and laparoscopy) as part of their standard of care.

You may qualify if:

• Subject provides informed consent
• Subject is \>18 years of age
• Subject is deemed competent for making medical decisions
• Subject is scheduled to undergo a staging pleuroscopy
• Subject is a surgical candidate
• A negative pregnancy test is required in women of child-bearing potential, as standard of care.

You may not qualify if:

• Subject is \<18 years old.

Sponsors & Collaborators

• Mayo Clinic: lead

Study Sites (1)

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Location

Related Links

• Mayo Clinic Clinical Trials

MeSH Terms

Conditions

Mesothelioma; Solitary Fibrous Tumor, Pleural

Condition Hierarchy (Ancestors)

Adenoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms; Neoplasms, Mesothelial; Solitary Fibrous Tumors; Neoplasms, Fibrous Tissue; Neoplasms, Connective Tissue; Neoplasms, Connective and Soft Tissue; Pleural Neoplasms; Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site

Study Officials

• Dennis Wigle, MD, PhD

  Mayo Clinic

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 20, 2015
• First Posted: January 7, 2016
• Study Start: January 15, 2016
• Primary Completion: April 22, 2023
• Study Completion: April 22, 2023
• Last Updated: January 13, 2025

Record last verified: 2025-01

Locations

US (1)