Caffeine Intake and Additive Effects on Cognition

NCT02647567 | Completed DMC

• 1 other identifier: UNIVERSO-03
• Study Type: interventional
• Target: 20
• Locations: 0 countries
• Sites: N/A

Brief Summary

Caffeine is a methylxanthine commonly consumed by the population for their psychostimulant properties, and their intake when in moderate doses seem to produce positive effects on stress, mood and memory. So, understanding that a positive effect of aerobic exercise can be displayed also on cognition, as caffeine, when in proper proportions, the investigators do not know if the joining of the two strategies into a single activity would be able to promote additional effects enhancing cognitive processes related to memory, attention, and motor reaction time.

Conditions

Healthy

Keywords

Cognitive; Aerobic Exercise; Performance

Outcome Measures

Primary Outcomes (3)

• Simple Reaction Time

  Acute Change from Baseline Psychomotor test to 1 min after aerobic exercise, and after 30 min

• Rey Auditory Verbal Learning Test

  Acute Change from Baseline Cognitive test to 1 min after aerobic exercise, and after 30 min

• Sustained Attention Test

  Acute Change from Baseline Cognitive test to 1 min after aerobic exercise, and after 30 min

Study Arms (2)

Caffeine Intake

EXPERIMENTAL

The experimental group ingest 500 mg of caffeine before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

Other: Caffeine Intake

Placebo Intake

PLACEBO COMPARATOR

The control group ingest 500 mg of placebo before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

Other: Placebo Intake

Interventions

Caffeine Intake OTHER

The experimental group ingest 500 mg of caffeine before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

Also known as: Caffeine

Caffeine Intake

Placebo Intake OTHER

The control group ingest 500 mg of placebo before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

Also known as: Placebo

Placebo Intake

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Fighting men
• Low levels of consumption of caffeine daily

You may not qualify if:

• Use more than 400 mg caffeine day
• Mental diseases
• Cognitive deficits

Sponsors & Collaborators

• Universidade Federal do Rio de Janeiro: lead

MeSH Terms

Interventions

Caffeine

Intervention Hierarchy (Ancestors)

Xanthines; Alkaloids; Heterocyclic Compounds; Purinones; Purines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, Fused-Ring

Study Officials

• Sérgio Machado, PhD

  Salgado de Oliveira University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctorade in Mental Health

Study Record Dates

• First Submitted: December 5, 2015
• First Posted: January 6, 2016
• Study Start: May 1, 2015
• Primary Completion: November 1, 2015
• Study Completion: December 1, 2015
• Last Updated: January 6, 2016

Record last verified: 2016-01