NCT02618863

Brief Summary

the investigators have observed that women may require less CF than men to occlude the esophageal entrance, and that the routine use of 30 N in women may actually increase the incidence of airway-related problems. The objective of the current investigation was to test this hypothesis. In this study, real-time visual and dynamic means were used to assess the effectiveness of different forces applied to the cricoid cartilage in occluding the esophageal entrance in men and women. The patency of the esophageal entrance was directly visualized using the Glidescope Video Laryngoscope in anesthetized and paralyzed patients with and without CP. Evidence of closure of the esophageal lumen was confirmed by the inability to introduce a gastric tube (GT) into the esophagus under direct vision. New method , using Cricometer , was used to measure the applied force .

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 23, 2015

Completed
8 days until next milestone

Study Start

First participant enrolled

December 1, 2015

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 2, 2015

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2016

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
Last Updated

February 17, 2016

Status Verified

February 1, 2016

Enrollment Period

2 months

First QC Date

November 23, 2015

Last Update Submit

February 15, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Necessary force of CP to occlude the esophagus in female versus male . an up and down method will define the CP 50 in each gender . A comparison between CP50 in both sex will define exactly our outcome : Is there a gender difference .

    24 hours

Study Arms (2)

1 , cricoid pressure

ACTIVE COMPARATOR

30 male

Device: Cricoid pressure

2,cricoid pressure

ACTIVE COMPARATOR

30 female

Device: Cricoid pressure

Interventions

Applying cricoid pressure and testing its effectiveness using gastric tube . in addition , by using the cricometer , the CP 50 is defined and compared in both gender

1 , cricoid pressure2,cricoid pressure

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • ASA 1 - 2
  • Easy Identification cricoid cartilage
  • No contre indication to CP

You may not qualify if:

  • obese patients
  • ASA2 \& ASA3
  • contre indication to CP

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Procare Riaya Hospital

Khobar, Estern, 31952, Saudi Arabia

Location

Related Publications (1)

  • Zeidan AM, Salem MR, Bamadhaj M, Mazoit JX, Sadek H, Houjairy H, Abdulkhaleq K, Bamadhaj N. The Cricoid Force Necessary to Occlude the Esophageal Entrance: Is There a Gender Difference? Anesth Analg. 2017 Apr;124(4):1168-1173. doi: 10.1213/ANE.0000000000001631.

Study Officials

  • kamal abdulkhaleq, MD

    Procare Riaya Hospital

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr.AHED ZEIDAN

Study Record Dates

First Submitted

November 23, 2015

First Posted

December 2, 2015

Study Start

December 1, 2015

Primary Completion

February 1, 2016

Study Completion

March 1, 2016

Last Updated

February 17, 2016

Record last verified: 2016-02

Locations