Effects of Protein Ingestion and Exercise Training on Muscular Performance

NCT02593656 | Completed

• 1 other identifier: 1401-382
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study systematically quantified the effects of a protein pacing energy and performance (IEPS) meal pattern compared to a standard recommended control (C) diet both of which were combined with a 4-day/week exercise training program on total and regional (abdominal) body composition (lean mass and fat mass), muscular strength and performance, flexibility, blood lipids and glucose, hormones, mood state and energy metabolism in 60 healthy middle-aged (25-55 years old) men and women following a 12-week intervention. Participants were enrolled in one of two cohorts:

1. 1.Experimental, 2g/kg/Body Weight (BW) Protein (IEPS) (n=30)
2. 2.Control, 1g/kg/Body Weight Protein (C) (n=30)

Conditions

Physical Performance

Keywords

protein ingestion; resistance exercise; interval exercise; stretching exercise; endurance exercise

Outcome Measures

Primary Outcomes (1)

• Muscular Strength and Power

  Changes in one repetition muscular strength and power of upper and lower body

  baseline and post 12 week intervention

Secondary Outcomes (1)

• Total and Regional Body Composition

  baseline and post 12 week intervention

Other Outcomes (3)

• Arterial function

  baseline and post 12 week intervention

• Blood Lipids

  baseline and post 12 week intervention

• Energy Metabolism

  baseline and post 12 week intervention

Study Arms (2)

High Protein

EXPERIMENTAL

Ingestion of 2.0 grams of protein per kilogram of body weight per day combined with exercise training

Behavioral: High Protein

Normal Protein

ACTIVE COMPARATOR

Ingestion of 1.0 gram of protein per kilogram of body weight per day combined with exercise training

Behavioral: Normal Protein

Interventions

High Protein BEHAVIORAL

Protein-pacing throughout the day and exercise training for 12 weeks

High Protein

Normal Protein BEHAVIORAL

Normal protein intake throughout the day and exercise training for 12 weeks

Normal Protein

Eligibility Criteria

• Age: 25 Years - 55 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Participants will be non-smoking, healthy, men and women with no known cardiovascular or metabolic diseases as assessed by a medical history and approval by their physicians to participate. All participants will be active (\>30 min, 4d/wk of structured physical activity \> 3 years) as assessed by a Physical Activity questionnaire, normal weight (BMI=20-27.5 kg/m2; % body fat\<30%), middle aged (25-55 years), and weight stable (+/-2kg) for at least 6 months prior to beginning the study

You may not qualify if:

• Individuals will be excluded from participation for the following reasons: orthopedic conditions that preclude or limit participation in the exercise training (RISE); history of cardiometabolic disease (e.g., diabetes, heart disease, etc.) and/or cancer; pregnant or may be pregnant; or allergic to milk products.

Sponsors & Collaborators

• Skidmore College: lead

Study Officials

• Paul J Arciero, Phd

  Skidmore College

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 29, 2015
• First Posted: November 2, 2015
• Study Start: January 1, 2015
• Primary Completion: May 1, 2015
• Study Completion: August 1, 2015
• Last Updated: May 2, 2022

Record last verified: 2022-04