NCT02592109

Brief Summary

The epidemic of pediatric obesity has become a public health burden in both developed and developing countries, due to its serious health consequences, including an increased risk of type 2 Diabetes Mellitus and heart disease. Currently, dietary and exercise changes are still the center of preventive and treatment measures of obesity. Recently, the omega-3 group, one of the groups of polyunsaturated fatty acids (PUFAs), has been associated with many positive effects leading to the improvement of many diseases related to obesity. Nevertheless, the consumption of this essential nutrient requires certain ration to optimize its favorable result. Although previous studies have examined the efficacy of dietary counseling approach as treatment for obesity, none of them as explicitly explore the use of linear programming to create a tailored diet containing high omega-3 fatty acid food as a part of dietary counseling in obesity management program among children. Thus, this study is intended to contribute the clinical evidence regarding this area of knowledge, specifically the effects of enhanced counseling containing complementary feeding recommendation on nutritional status, omega-3 fatty acid, malondialdehyde, and alpha Tocopherol among children with risk of overweight aged 12 -23 months in East Jakarta.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
38

participants targeted

Target at P25-P50 for phase_2

Timeline
Completed

Started Nov 2015

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 29, 2015

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 30, 2015

Completed
2 days until next milestone

Study Start

First participant enrolled

November 1, 2015

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
Last Updated

June 22, 2016

Status Verified

June 1, 2016

Enrollment Period

4 months

First QC Date

October 29, 2015

Last Update Submit

June 21, 2016

Conditions

Keywords

Complementary Feeding RecommendationLinear ProgrammingNutritional StatusOmega-3 Fatty AcidsMalondialdehydealpha-Tocopherol

Outcome Measures

Primary Outcomes (1)

  • Nutritional status

    Body weight and body height will be used to calculate body mass index

    10 weeks

Secondary Outcomes (3)

  • Omega-3 Fatty Acid in plasma

    10 weeks

  • Malondialdehyde plasma

    10 weeks

  • alpha-Tocopherol plasma

    10 weeks

Study Arms (2)

Enhanced Counseling using CFR based on LP

EXPERIMENTAL

The counseling will be done by individual face-to-face communications. The intervention's arm will get a counseling with an additional of 7-day cycle with adequate n-3 and optimal n-3/6 ratio for complementary feeding menu obtained from linear programming formulation. The counseling consisted of nutritional status in children aged 12-23 months and how to determine the nutritional status; the principle of balanced diet; definition, function, and source of omega-3; example of menu that contains adequate omega-3. The duration of counseling is approximately 30 minutes, once a week for ten weeks. The mother or caregiver will also receive daily menu for seven days that should be followed during the intervention. The daily menu comprised of 3 main meals and 2 snacks.

Behavioral: Enhanced Counseling using CFR based on Linear Programming

General CFR Counseling

ACTIVE COMPARATOR

The control's arm will get general counseling combining balance diet and IYCF principal, which already been used by Ministry of Health, with additional of 7-day cycle menu guidance modified from existing or available menu which can be downloaded for public on Ministry of Health official website. The counseling consisted of nutritional status in children aged 12-23 months and how to determine the nutritional status; the principle of balanced diet based on Ministry of Health's Recommendation, and example of balanced diet menu. The duration of counseling is approximately 30 minutes, once a week for ten weeks. The mother or caregiver will also receive daily menu for seven days that should be followed during the intervention. The daily menu comprised of 3 main meals and 2 snacks.

Behavioral: Enhanced Counseling using CFR based on Linear Programming

Interventions

Enhanced Counseling using CFR based on LPGeneral CFR Counseling

Eligibility Criteria

Age12 Months - 24 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • aged 12-23 months old at first counseling
  • body mass index more than +1 standard deviation in WHO Z-score
  • parent agree to participate in the study by signing informed consent

You may not qualify if:

  • Children with congenital disease and serious diseases
  • Children with parent/caregiver who is illiterate
  • Children with parent/caregiver who had communication disability

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Posyandu di Kelurahan Pisangan Timur, Cipinang, Kayuputih, Rawamangun

Jakarta, DKI Jakarta, Indonesia

Location

MeSH Terms

Conditions

Overweight

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. dr. MS SpGK

Study Record Dates

First Submitted

October 29, 2015

First Posted

October 30, 2015

Study Start

November 1, 2015

Primary Completion

March 1, 2016

Study Completion

March 1, 2016

Last Updated

June 22, 2016

Record last verified: 2016-06

Locations