Prospective Population Based Cohort Study on Cognitive and Cardiovascular Aging (MonaLisaPredor)
MLP
2 other identifiers
observational
520
1 country
1
Brief Summary
Aging is a long term process, starting early in life, and progressively affecting various functions and organs. Cardiovascular diseases and cognitive impairment are two conditions related to advancing age and sharing common risk factors. The Mona Lisa- PREDOR study is a population-based prospective cohort study carried out to develop risk prediction algorithms aimed at identifying people who are the most likely to develop impaired psychometric and cognitive functioning and impaired cardiovascular risk, in the coming years.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2013
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 22, 2013
CompletedFirst Submitted
Initial submission to the registry
May 24, 2013
CompletedFirst Posted
Study publicly available on registry
October 2, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2018
CompletedJuly 31, 2020
July 1, 2020
4.9 years
May 24, 2013
July 29, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Test of memorizing and restitution of words
French version of the Rey auditory verbal learning test
7 years after the first assessment
Secondary Outcomes (4)
Level of cardiovascular risk
7 years after the first assessment
Level of cardiovascular risk
10 years after the first assessment
WAIS-DSST
7 years after the first assessment
Stroop test
7 years after the first assessment
Eligibility Criteria
The design is a prospective cohort study carried out among 1500 men and women from the general population, aged 42-89 years,and living in South-western France. Except for participants aged 80-89 years, all participants have been previously assessed in 2005-2007, as regard to their psychometric and cognitive performances and level of cardiovascular risk, as part of the Mona Lisa study.
You may qualify if:
- Men and women aged 42-79 years, living in South-western France, who participated in the Mona Lisa Study (2005-2007) (in the Mona Lisa study, participants were selected by drawing on polling lists)
- Men and women aged 80-89 years, living in South-western France, selected by drawing on polling lists.
You may not qualify if:
- Subject who refuses to participate (who refuses to sign the inform consent)
- Subject not affiliated to a health assurance system
- Subject with altered cognitive functioning compromising the understanding of the information on the study, and not accompanied by a trusted third party.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Toulouse University Hospital
Toulouse, 31400, France
Biospecimen
Blood
Study Officials
- PRINCIPAL INVESTIGATOR
Vanina BONGARD, MD, PhD
University Hospital, Toulouse
- STUDY CHAIR
Jean FERRIERES, MD PhD
University Hospital, Toulouse
- STUDY CHAIR
Bruno VELLAS, MD PhD
University Hospital, Toulouse
- STUDY CHAIR
Jean-Bernard RUIDAVETS, MD
University Hospital, Toulouse
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 24, 2013
First Posted
October 2, 2015
Study Start
May 22, 2013
Primary Completion
May 1, 2018
Study Completion
June 1, 2018
Last Updated
July 31, 2020
Record last verified: 2020-07