Head and Neck Cancer in Children: A Retrospective Study

NCT02557048 | Unknown

• 1 other identifier: Ped Head Neck Malig
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to identify demographic characteristics, various histopathologies, and site preferences for each disease entity of malignant head and neck tumors in pediatric oncology patients \& treatment outcomes in these patients, according to experience at South Egypt Cancer Institute which is the largest referral site in Upper Egypt.

Conditions

Head and Neck Neoplasms; Cancer of Head and Neck; Cancer of the Head and Neck; Head and Neck Cancer; Neoplasms, Head and Neck

Keywords

Childhood Cancer; Head and Neck Tumors; Pediatric Oncology

Outcome Measures

Primary Outcomes (2)

• Overall survival (OS)

  Time from the date of initiation of treatment until death from any cause

  Participants will be retrospectively followed forward in time from the date of initiation of treatment till the primary completion date of the study, an expected average of 5 years

• Event Free Survival (EFS)

  Time from the date of initiation of treatment until disease progression, or death for any reason.

  Participants will be retrospectively followed forward in time from the date of initiation of treatment till the primary completion date of the study, an expected average of 5 years

Eligibility Criteria

• Age: Up to 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

A hospital-based study, involving Pediatric cancer patients, those diagnosed with malignant tumors of the head \& neck, in the period from 2001 January till 2015 December, and received treatment at the pediatric oncology department, their medical reports will be retrospectively reviewed for data collection.

You may qualify if:

• Patients whose age less than 19 years.
• Patients diagnosed with a primary malignant tumor of the head \& neck.

You may not qualify if:

• Patients whose age more than 18 years.
• Patients diagnosed with a malignant disease primarily arising from the bone marrow.
• Patients diagnosed with tumors of the central nervous system.
• Patients diagnosed with retinoblastoma.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut University

Asyut, 71515, Egypt

RECRUITING

Related Publications (2)

• Chadha NK, Forte V. Pediatric head and neck malignancies. Curr Opin Otolaryngol Head Neck Surg. 2009 Dec;17(6):471-6. doi: 10.1097/MOO.0b013e3283323893.

  PMID: 19745735 BACKGROUND

• Gosepath J, Spix C, Talebloo B, Blettner M, Mann WJ. Incidence of childhood cancer of the head and neck in Germany. Ann Oncol. 2007 Oct;18(10):1716-21. doi: 10.1093/annonc/mdm278. Epub 2007 Jul 28.

  PMID: 17660492 BACKGROUND

MeSH Terms

Conditions

Head and Neck Neoplasms; Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Site

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer, Pediatric Oncology Department

Study Record Dates

• First Submitted: September 21, 2015
• First Posted: September 22, 2015
• Study Start: January 10, 2019
• Primary Completion: November 1, 2023
• Study Completion: December 1, 2023
• Last Updated: July 24, 2023

Record last verified: 2023-07

Locations

EG (1)