Key Insights

Highlights

Success Rate

73% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 42/100

Termination Rate

21.1%

4 terminated out of 19 trials

Success Rate

73.3%

-13.2% vs benchmark

Late-Stage Pipeline

26%

5 trials in Phase 3/4

Results Transparency

73%

8 of 11 completed with results

Key Signals

8 with results73% success

Data Visualizations

Phase Distribution

17Total
Not Applicable (2)
P 1 (2)
P 2 (8)
P 3 (5)

Trial Status

Completed11
Terminated4
Active Not Recruiting2
Unknown1
Recruiting1

Trial Success Rate

73.3%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (19)

Showing 19 of 19 trials
NCT06062420Phase 2Active Not RecruitingPrimary

A Platform Study of Novel Immunotherapy Combinations as First-Line Treatment in Participants With PD-L1 Positive Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck- GALAXIES H&N-202

NCT02296684Phase 2Completed

Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma

NCT06790966Phase 3Active Not Recruiting

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

NCT04260126Phase 2Completed

Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC

NCT06256588Phase 3RecruitingPrimary

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

NCT02573493Phase 2Completed

Nab-Paclitaxel and Cisplatin or Nab-paclitaxel as Induction Therapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck (HNSCC)

NCT04428333Phase 3TerminatedPrimary

Study of GSK3359609 With Pembrolizumab and 5-fluorouracil (5-FU)-Platinum Chemotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

NCT04128696Phase 3TerminatedPrimary

Study of GSK3359609 and Pembrolizumab in Programmed Death Receptor 1-ligand 1 (PD-L1) Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

NCT02557048Unknown

Head and Neck Cancer in Children: A Retrospective Study

NCT02376699Phase 1Terminated

Safety Study of SEA-CD40 in Cancer Patients

NCT03178110Not ApplicableCompletedPrimary

Manual Therapy and Use of the Dynasplint for Trismus in Patients With Head and Neck Cancer

NCT01116336Phase 1Completed

Phase I Chemoprevention Trial With Green Tea Polyphenon E & Erlotinib in Patients With Premalignant Lesions of the Head & Neck

NCT03356093CompletedPrimary

Change in Symptom Clusters in HNC Patients

NCT00725764Phase 2CompletedPrimary

Phase 2 Study of GSK1363089 (Formerly XL880) in Adults With Squamous Cell Cancer of the Head and Neck

NCT00798655Phase 2Completed

Trial of Postoperative Radiation, Cisplatin, and Panitumumab in Locally Advanced Head and Neck Cancer

NCT00387127Phase 2CompletedPrimary

Lapatinib Versus Placebo Given Concurrently With Cisplatin And Radiotherapy In Patients With Unresected Head And Neck Cancer

NCT00424255Phase 3CompletedPrimary

Study Of Adjuvant Lapatinib In High-Risk Head And Neck Cancer Subjects After Surgery

NCT01370876Phase 2Terminated

Efficacy and Safety Study of Oxaliplatin/5-FU in Patients With Recurrent or Metastatic Head and Neck Cancer

NCT01110980Not ApplicableCompletedPrimary

Normalcy of Food Intake in Head and Neck Cancer Patients

Showing all 19 trials

Research Network

Activity Timeline