Key Insights

Highlights

Success Rate

83% trial completion

Published Results

253 trials with published results (16%)

Research Maturity

816 completed trials (51% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

10.4%

168 terminated out of 1609 trials

Success Rate

82.9%

-3.6% vs benchmark

Late-Stage Pipeline

8%

129 trials in Phase 3/4

Results Transparency

31%

253 of 816 completed with results

Key Signals

253 with results83% success168 terminated

Data Visualizations

Phase Distribution

1,283Total
Not Applicable (407)
Early P 1 (36)
P 1 (319)
P 2 (392)
P 3 (104)
P 4 (25)

Trial Status

Completed816
Recruiting233
Unknown175
Terminated168
Active Not Recruiting78
Withdrawn68

Trial Success Rate

82.9%

Benchmark: 86.6%

Based on 816 completed trials

Clinical Trials (1609)

Showing 20 of 20 trials
NCT07667400Phase 1Not Yet RecruitingPrimary

Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer

NCT04609280Phase 2Active Not RecruitingPrimary

Selective Avoidance of Nodal VolumEs at Minimal Risk (GCC 20110)

NCT07759193Not ApplicableRecruiting

Energy Expenditure Assessment in Head and Neck Cancer Patients Treated With Free Flap Surgery

NCT04044859Phase 1Active Not Recruiting

ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)

NCT07631650Phase 2Not Yet Recruiting

Bevonescein for Improved Intraoperative Nerve Visualization to Improve Voice Outcomes in Thyroidectomy Patients

NCT06531083Not ApplicableRecruitingPrimary

Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus

NCT05544136Phase 2RecruitingPrimary

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

NCT06289049Phase 2Completed

Heavy Strength Training in Head and Neck Cancer Survivors

NCT05273307Phase 3Active Not RecruitingPrimary

Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy

NCT03708224Phase 2Active Not Recruiting

Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck

NCT06172478Phase 2Recruiting

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

NCT06666881Not ApplicableRecruitingPrimary

Skeletal Muscle Mass Changes on Images for Prediction of Prognosis After Exercise Training in HNSCC Patients

NCT06145412Phase 2CompletedPrimary

A Study of Xevinapant With Cisplatin and Radiation Therapy After Surgery in People With Head and Neck Cancer

NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT07752875Phase 1Not Yet Recruiting

A Study of LG00313112 in Participants With Advanced Solid Malignancies Harboring a TP53 Y220C Mutation

NCT06674499Not ApplicableCompletedPrimary

Development and Evaluation of a Self-Management Model for Cancer Rehabilitation

NCT05995821RecruitingPrimary

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

NCT05650710Not ApplicableCompletedPrimary

Intraoperative Ansa Cervicalis Nerve (ACN) Stimulation

NCT02489084CompletedPrimary

Predictive Models for Radiation-induced Side Effects in Head and Neck Cancer Based on Single Nucleotide Polymorphisms (SNP)

NCT07110142Not ApplicableRecruiting

Tongue Proactive Strengthening Exercise Program Following Partial/Hemi Glossectomy and Reconstruction

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