Key Insights

Highlights

Success Rate

83% trial completion

Published Results

256 trials with published results (16%)

Research Maturity

822 completed trials (51% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

10.4%

168 terminated out of 1615 trials

Success Rate

83.0%

-3.6% vs benchmark

Late-Stage Pipeline

8%

129 trials in Phase 3/4

Results Transparency

31%

256 of 822 completed with results

Key Signals

256 with results83% success168 terminated

Data Visualizations

Phase Distribution

1,289Total
Not Applicable (410)
Early P 1 (36)
P 1 (319)
P 2 (395)
P 3 (104)
P 4 (25)

Trial Status

Completed822
Recruiting238
Unknown173
Terminated168
Active Not Recruiting76
Withdrawn70

Trial Success Rate

83.0%

Benchmark: 86.6%

Based on 822 completed trials

Clinical Trials (1615)

Showing 20 of 20 trials
NCT07667400Phase 1Not Yet RecruitingPrimary

Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer

NCT04585750Phase 1Recruiting

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

NCT06472726Not ApplicableTerminatedPrimary

Mental Health App for Cancer Survivors Study

NCT07059884Not ApplicableRecruiting

Distance-Based Exercise to Preserve Function and Prevent Disability

NCT03082534Phase 2Completed

Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

NCT06997068Phase 2Recruiting

Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population

NCT05816785Early Phase 1CompletedPrimary

Pilot Study of Imatinib Cetuximab Combo for H & N Cancer

NCT07852949Not ApplicableNot Yet RecruitingPrimary

Understanding the Role of MyCareGorithm as a Visual Digital Platforms in Cancer Treatment Education and Patient Comprehension of Oncology Treatment Plans

NCT06172478Phase 2Recruiting

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

NCT07090499Phase 1Recruiting

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

NCT03170960Phase 1Active Not Recruiting

Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

NCT07085091Phase 1Recruiting

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

NCT03358472Phase 3CompletedPrimary

Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)

NCT05287113Phase 2CompletedPrimary

Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-Line Treatment in Participants With PD-L1-Positive (CPS ≥ 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

NCT02994069Phase 2Active Not Recruiting

Cisplatin + Radiation in SCCHN and Correlation With Oxidative Stress Markers

NCT03702309Recruiting

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

NCT06667427Not ApplicableRecruiting

Pilot Study of Management of Facial Paralysis in the Oncologic Patient: Nerve Transfer Techniques to Improve Facial Function and Quality of Life

NCT07124000Recruiting

DESTINY-PANTUMOUR04

NCT07838090Not ApplicableNot Yet RecruitingPrimary

Resistance Training and Creatine Supplementation for Head and Neck Cancer

NCT04044859Phase 1Active Not Recruiting

ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)

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Research Network

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