NCT02544672

Brief Summary

The objective of this study is to evaluate the functional benefits of a myoelectric Elbow-Wrist-Hand orthosis for persons with upper limb paralysis caused by a cerebrovascular accident (CVA).

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2015

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 1, 2015

Completed
8 days until next milestone

First Posted

Study publicly available on registry

September 9, 2015

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2016

Completed
Last Updated

September 9, 2015

Status Verified

September 1, 2015

Enrollment Period

1 year

First QC Date

September 1, 2015

Last Update Submit

September 4, 2015

Conditions

Outcome Measures

Primary Outcomes (3)

  • Fugl-Meyer Assessment Upper Extremity (FMA-UE)

    Assessment of sensorimotor function for the upper extremities (arms) http://www.rehabmeasures.org/lists/rehabmeasures/dispform.aspx?ID=908

    2 hours

  • Modified Ashworth Scale

    Measurement of muscle spasticity due to nervous system injury or disease http://www.rehabmeasures.org/Lists/RehabMeasures/PrintView.aspx?ID=902

    2 hours

  • Box and Blocks Test

    An assessment of unilateral gross manual dexterity, measured by the number 1 inch cubes an individual can move over a barrier in a 60 second time period. http://www.rehabmeasures.org/Lists/RehabMeasures/DispForm.aspx?ID=917

    2 hours

Study Arms (1)

Myoelectric Elbow-Wrist-Hand Orthosis

EXPERIMENTAL
Device: Myoelectric Elbow-Wrist-Hand orthosis

Interventions

An arm orthosis that uses myoelectric signals to control the level of mechanical assistance provided to a user's elbow and hand in order to overcome upper limb weakness or paralysis and achieve functional tasks.

Also known as: MyoPro®
Myoelectric Elbow-Wrist-Hand Orthosis

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adults over 18 years.
  • Upper limb impairment caused by any stroke (CVA)
  • Minimum of trace MMT (1/5) in Biceps and/or Triceps
  • Full Passive range of motion in elbow, forearm, wrist, and hand
  • Active shoulder flexion of at least 30 degrees of shoulder abduction of at least 20 degrees
  • Score of at least 20 on the Mini Mental Status Examination.
  • Ability to read and comprehend the English language.
  • Ability to generate consistent, detectable EMG signal from the upper arm and forearm sensor sites with wrist in neutral or flexed positions.

You may not qualify if:

  • Fixed upper limb contractures on affected side.
  • Subjects with severe spasticity or tone (defined as 3 or more on the Modified Ashworth Scale).
  • Inability to follow three step directions.
  • Severe shoulder subluxation, pain or shoulder dislocation.
  • Passive shoulder range of motion less than 45 degrees in flexion and abduction.
  • Pain or hypersensitivity in the arm(s)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

GRE Chardon

Chardon, Ohio, 44024, United States

RECRUITING

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Central Study Contacts

Jonathan Naft, CPO, LPO

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 1, 2015

First Posted

September 9, 2015

Study Start

July 1, 2015

Primary Completion

July 1, 2016

Last Updated

September 9, 2015

Record last verified: 2015-09

Locations