NCT02541630

Brief Summary

A variety of mindfulness-based interventions, such as Mindfulness-Based Stress Reduction and Mindfulness-Based Cognitive Therapy have been shown to be beneficial for individuals experiencing mood and anxiety symptoms. The aim of this pilot study is to test the feasibility of using a similar intervention, known as Big Mind, for veterans with PTSD and other psychological symptoms. Big Mind is a method of self-exploration that utilizes a voice dialog technique to help individuals see the world and themselves from a variety of perspectives. The investigators hypothesize that this process will increase mindfulness and decrease self-referential thinking, which is associated with negative affect. To test the feasibility of using this method, veterans with PTSD will complete a four-week group Big Mind class with a total of four sessions. The investigators will use a single group design with pre and post-intervention measures to assess tolerability and acceptance of the intervention. Secondary outcome measures will evaluate symptom improvement and increased mindfulness. If this project demonstrates that using this intervention for veterans with PTSD is feasible, then more rigorous clinical trials will be warranted.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Aug 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2015

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

August 27, 2015

Completed
8 days until next milestone

First Posted

Study publicly available on registry

September 4, 2015

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2016

Completed
Last Updated

April 28, 2016

Status Verified

April 1, 2016

Enrollment Period

8 months

First QC Date

August 27, 2015

Last Update Submit

April 26, 2016

Conditions

Keywords

Mindfulness

Outcome Measures

Primary Outcomes (1)

  • Feasibility

    The investigators will assess tolerability and acceptance of the intervention via subjective feedback from each participant at the end of week 4, and monitor drop out rates.

    4 weeks

Secondary Outcomes (5)

  • Improvement of PTSD symptoms

    4 weeks

  • Increase in mindfulness

    4 weeks

  • Improvement of depressive symptoms

    4 weeks

  • Improvement of anxiety

    4 weeks

  • Improvement of sleep

    4 weeks

Interventions

Big MindBEHAVIORAL

mindfulness based intervention

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • male and female veterans with PTSD
  • age 18 - 65
  • ability to provide informed consent

You may not qualify if:

  • diagnosis of any psychotic disorder
  • psychotic symptoms secondary to a mood disorder or other condition
  • diagnosis of cognitive impairment or dementia
  • currently on facility suicide high-risk list
  • pregnancy
  • impaired decision-making capacity

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

George E. Whalen VAMC

Salt Lake City, Utah, 84108, United States

Location

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
FED
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident Physician

Study Record Dates

First Submitted

August 27, 2015

First Posted

September 4, 2015

Study Start

August 1, 2015

Primary Completion

April 1, 2016

Study Completion

April 1, 2016

Last Updated

April 28, 2016

Record last verified: 2016-04

Locations