NCT02780635

Brief Summary

In layperson's language state the purpose of the study in 3-5 sentences. Previous research has demonstrated that intimate partners can positively influence those with PTSD to seek treatment. The investigators have preliminary evidence to demonstrate that mobile apps, such as PTSD Coach can be helpful for those with PTSD, and the current study will provide Veterans with PTSD and their partners with a mobile app designed to promote engagement with evidence-based treatments for PTSD. The purpose of this PILOT study is to evaluate methods for delivering a couples-based intervention to reduce PTSD symptoms and improve relationship quality in Veterans and their intimate partners. b) State what the Investigator(s) hope to learn from the study. Include an assessment of the importance of this new knowledge. Understanding ways to improve the public health impact of public-facing, evidence-based mobile apps is critical. This study will test a low-cost, "high-touch" approach to improving the outcomes associated with use of the PTSD Coach and PTSD Family Coach mobile apps,which are already available to the general public and used by over 55,000 new users per year.This study will test whether the involvement of an intimate partner in the use of a mobile app for PTSD will result in changes in how the mobile apps are used and in relationship quality and PTSD symptoms over time. Additionally, this study will test whether the addition of a discussion board can improve engagement with the apps and/or outcomes. The study will also provide useful qualitative data that can inform the development of subsequent dyadic interventions using mobile technologies. c) Explain why human subjects must be used for this project. (i.e. purpose of study is to test efficacy of investigational device in individuals with specific condition; purpose of study is to examine specific behavioral traits in humans in classroom or other environment) The purpose of this study is to evaluate how Veterans and their partners interact with evidence-based mobile apps for improving PTSD symptoms.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
152

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2015

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

May 4, 2016

Completed
19 days until next milestone

First Posted

Study publicly available on registry

May 23, 2016

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

April 26, 2019

Status Verified

April 1, 2019

Enrollment Period

3 years

First QC Date

May 4, 2016

Last Update Submit

April 24, 2019

Conditions

Keywords

family, caregiving, ptsd, couples

Outcome Measures

Primary Outcomes (7)

  • Caregiver Burden

    Montgomery Burden Interview

    10 weeks

  • Functional Well-Being

    Partner-rated Interpersonal Well-Being Scale

    10 weeks

  • Personal Health Questionnaire Depression Scale

    8 Item scale measuring depression.

    10 weeks

  • Generalized Anxiety Symptoms

    Generalized Anxiety Disorder-7 Scale (GAD-7)

    10 weeks

  • PTSD Symptoms

    5 Item Partner-rated Posttraumatic Stress Disorder Checklist-5 (PCL-5)

    10 weeks

  • Positive Relationship Behaviors

    Author-constructed relationship behaviors scale

    10 weeks

  • Stress

    Perceived Stress Scale

    10 weeks

Secondary Outcomes (4)

  • Emotional Intimacy

    10 weeks

  • Caregiving Self-Efficacy Scale

    10 weeks

  • Positive Partner Communication

    10 weeks

  • Relationship Self-Efficacy

    10 weeks

Study Arms (2)

App + Couples Coach Intervention

EXPERIMENTAL

Both members of the couple will receive a mobile app for PTSD: PTSD Coach for the Veteran and PTSD Family Coach for the partner/spouse. Those assigned to this arm will also receive mailed materials that are designed to help increase positive communication strategies.

Behavioral: Mobile App + Mailed Materials for managing stress associated with PTSDBehavioral: Mobile App for managing stress associated with PTSD

App Alone

ACTIVE COMPARATOR

Both members of the couple will receive a mobile app for PTSD: PTSD Coach for the Veteran and PTSD Family Coach for the partner/spouse.

Behavioral: Mobile App for managing stress associated with PTSD

Interventions

PTSD Coach and PTSD Family Coach mobile apps plus mailed "Couples Coach" intervention materials and discussion board added to PTSD Family Coach app

App + Couples Coach Intervention

PTSD Coach and PTSD Family Coach mobile apps

App + Couples Coach InterventionApp Alone

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • To be eligible to participate, participants must be either a Veteran with PTSD or living with a partner who is a Veteran with PTSD.
  • Veterans must be:
  • A veteran of the U.S. Armed Forces
  • Must have a previous diagnosis of PTSD
  • Must have access to a smart phone using the iOS operating system
  • Must not have previously used PTSD Coach.
  • Partners of Veterans must be:
  • An intimate partner of a Veteran
  • Living with that partner
  • Must have access to a smart phone using the iOS operating system
  • must be experiencing significant stress

You may not qualify if:

  • a) actual or threatened interpersonal violence in the home

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA Palo Alto Health Care System Menlo Park Division

Menlo Park, California, 94025, United States

Location

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
FED
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Psychologist

Study Record Dates

First Submitted

May 4, 2016

First Posted

May 23, 2016

Study Start

December 1, 2015

Primary Completion

December 1, 2018

Study Completion

December 1, 2018

Last Updated

April 26, 2019

Record last verified: 2019-04

Locations