NCT02521909

Brief Summary

The purpose of this study is to compare the accuracy of different apex locators. Before root canal therapy, dentists use a device called an electronic apex locator (EAL) to measure the root canal and to locate its opening at the tip of the tooth's root (called the apical foramen). A root canal is the space inside the root of a tooth. If the tissue within the root canal becomes infected, dentists may perform root canal therapy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 7, 2015

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 13, 2015

Completed
19 days until next milestone

Study Start

First participant enrolled

September 1, 2015

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 21, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 21, 2017

Completed
Last Updated

June 22, 2017

Status Verified

June 1, 2017

Enrollment Period

1.8 years

First QC Date

August 7, 2015

Last Update Submit

June 21, 2017

Conditions

Keywords

Root Canal lengthElectronic apex locatorEndodontics

Outcome Measures

Primary Outcomes (1)

  • Tooth Length Measurement after extraction

    A Kodak 9000 3D is used as a small-volume field of view (FOV) CBCT based on its scan to allow cone beam reconstructions at 0.076 mm with a minimal discrepancy compared to histologic sections. The extracted teeth are imaged and slices reviewed for accuracy

    48 hours After Extraction

Study Arms (1)

Tooth Extraction

Intervention is Tooth Extraction for Assessment of Different Apex Locators. All people in the study will contribute one or more teeth, which will be extracted for other clinical purposes, for device comparative testing

Device: ProMark (Tooth Extraction for Assessment of Different Apex Locators)Device: Root ZX II (Tooth Extraction for Assessment of Different Apex Locators)Device: NRG Rider (Tooth Extraction for Assessment of Different Apex Locators)

Interventions

The purpose of this study is to compare the accuracy of different apex locators on teeth that are scheduled for extractions. Before root canal therapy, dentists use a device called an electronic apex locator (EAL) to measure the root canal and to locate its opening at the tip of the tooth's root (called the apical foramen). A root canal is the space inside the root of a tooth. If the tissue within the root canal becomes infected, dentists may perform root canal therapy.

Tooth Extraction

The purpose of this study is to compare the accuracy of different apex locators on teeth that are scheduled for extractions. Before root canal therapy, dentists use a device called an electronic apex locator (EAL) to measure the root canal and to locate its opening at the tip of the tooth's root (called the apical foramen). A root canal is the space inside the root of a tooth. If the tissue within the root canal becomes infected, dentists may perform root canal therapy.

Tooth Extraction

The purpose of this study is to compare the accuracy of different apex locators on teeth that are scheduled for extractions. Before root canal therapy, dentists use a device called an electronic apex locator (EAL) to measure the root canal and to locate its opening at the tip of the tooth's root (called the apical foramen). A root canal is the space inside the root of a tooth. If the tissue within the root canal becomes infected, dentists may perform root canal therapy.

Tooth Extraction

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Individuals in need of extraction of multi-rooted teeth

You may qualify if:

  • Be an adult over 18 years of age.
  • Multi-rooted teeth (molar or premolar) scheduled for extraction because of non-restorability, orthodontic or periodontal reasons
  • Be able to understand and provide informed consent for participation in the protocol

You may not qualify if:

  • Any liver, kidney, heart, blood, metabolic or systemic disease which may make execution of the protocol or interpretation of the results difficult
  • History of syphilis, HIV, Hepatitis B or Hepatitis C
  • Pregnant
  • Currently receiving radiation
  • Any other medical/physical condition the PI deems unacceptable for participation.
  • Patient unable to provide informed consent
  • Plan to participate in another clinical trial within 30 days of entrance into this study
  • Tooth with "non-intact crown"
  • Presence of an electronic implantable device (pacemaker, etc)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

U of Michigan School of Dentistry

Ann Arbor, Michigan, 48109, United States

Location

MeSH Terms

Conditions

Dental Pulp Diseases

Interventions

Tooth Extraction

Condition Hierarchy (Ancestors)

Tooth DiseasesStomatognathic Diseases

Intervention Hierarchy (Ancestors)

Oral Surgical ProceduresSurgical Procedures, OperativeDentistry

Study Officials

  • Neville McDonald, BDS, MS

    University of Michigan

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Professor, Director of Endodontics

Study Record Dates

First Submitted

August 7, 2015

First Posted

August 13, 2015

Study Start

September 1, 2015

Primary Completion

June 21, 2017

Study Completion

June 21, 2017

Last Updated

June 22, 2017

Record last verified: 2017-06

Data Sharing

IPD Sharing
Will not share

Locations