NCT02503098

Brief Summary

This study will augment an existing mobile application for individuals with eating disorders by developing adaptive, tailored content targeting remediation of cognitive distortions. The adaptive application will be deployed and assessed for efficacy relative to the standard product in a randomized controlled trial.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,340

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2016

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 15, 2015

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 20, 2015

Completed
1.3 years until next milestone

Study Start

First participant enrolled

November 23, 2016

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 13, 2018

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 13, 2018

Completed
Last Updated

October 6, 2020

Status Verified

October 1, 2020

Enrollment Period

1.6 years

First QC Date

July 15, 2015

Last Update Submit

October 5, 2020

Conditions

Keywords

Eating DisordersCognitive Behavioral TherapyMobile PhoneSmartphoneAppBinge Eating DisorderBulimia NervosaSignal Detection Analysis

Outcome Measures

Primary Outcomes (1)

  • Changes in Eating Disorder Severity

    Self-reported eating disorder symptom severity. To measure changes in eating disorder severity over time, the Eating Disorder Evaluation Questionnaire (EDE-Q) will be used.

    Measured at the start of treatment (baseline), week 4, week 8 and 6 months follow-up

Secondary Outcomes (5)

  • Binge eating and purging episode frequency

    Measured at the start of treatment (baseline), week 4, week 8 and 6 months follow-up

  • Changes in Clinical Impairment Severity

    Measured at the start of treatment (baseline), week 4, week 8 and 6 months follow-up

  • Participant Satisfaction

    Participants will be followed for the duration of the 8-week trial

  • Adherence to the mobile application intervention

    Measured from the start of application utilization (baseline) to 8-weeks

  • Adherence to self-monitoring tasks

    Measured from the start of application utilization (baseline) to 8-weeks

Study Arms (2)

Recovery Record adaptive smartphone application (RR-A)

EXPERIMENTAL

Participants will have access to all Recovery Record standard functions and will additionally receive tailored, algorithm-generated content targeting cognitive distortions.

Behavioral: Recovery Record adaptive smartphone application

Recovery Record standard smartphone application (RR-S)

ACTIVE COMPARATOR

Participants will have access to all Recovery Record standard functions, including meal monitoring, motivational enhancement, social support, and coping skill strategies.

Behavioral: Recovery Record standard smartphone application

Interventions

Recovery Record adaptive smartphone application (RR-A)
Recovery Record standard smartphone application (RR-S)

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Meets criteria for clinically significant symptoms of eating disorder using self-report measures
  • Has an Android or iPhone and is willing to use phone for the study
  • Is able to speak and read English
  • Lives within the United States of America
  • Is at least 16 years of age

You may not qualify if:

  • Has visual, hearing, voice, or motor impairment that would prevent completion of study and treatment procedures
  • Has any psychiatric condition for which participation in a clinical trial of psychotherapy may be either inappropriate or dangerous (e.g., psychotic disorders, bipolar disorders, severe post traumatic stress disorder, etc.).
  • Exhibits severe suicidality, including ideation, plan, and intent.
  • Currently receiving weekly psychotherapy or planning to receive weekly psychotherapy for eating disorder during the 12 weeks of the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Recovery Record Research

San Francisco, California, 94107, United States

Location

Stanford University School of Medicine, Department of Psychiatry and Behavioral Sciences

Stanford, California, 94304, United States

Location

Related Publications (1)

  • Tregarthen J, Paik Kim J, Sadeh-Sharvit S, Neri E, Welch H, Lock J. Comparing a Tailored Self-Help Mobile App With a Standard Self-Monitoring App for the Treatment of Eating Disorder Symptoms: Randomized Controlled Trial. JMIR Ment Health. 2019 Nov 21;6(11):e14972. doi: 10.2196/14972.

Related Links

MeSH Terms

Conditions

Feeding and Eating DisordersBinge-Eating DisorderBulimia NervosaAlzheimer Disease

Condition Hierarchy (Ancestors)

Signs and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and SymptomsMental DisordersDementiaBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative DiseasesNeurocognitive Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 15, 2015

First Posted

July 20, 2015

Study Start

November 23, 2016

Primary Completion

July 13, 2018

Study Completion

September 13, 2018

Last Updated

October 6, 2020

Record last verified: 2020-10

Locations