Topiramate for Binge Eating Disorder Among Adolescents

NCT00768677 | Completed

• 1 other identifier: 03-04-063
• Study Type: interventional
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

This is a study of topiramate to see whether topiramate decreases binge eating behavior among adolescents and young adults. The investigators did also checked whether topiramate affected cognitive function or not.

Conditions

Eating Disorders; Bulimia Nervosa

Keywords

binge eating behavior; adolescents

Interventions

topiramate DRUG

Eligibility Criteria

• Age: 12 Years - 23 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Subjects (aged 12 to 23) were included if they
• Met the criteria of bulimia nervosa or eating disorder NOS with binge-eating behavior in DSM-IV-TR,
• Had weight \> or = 100th % of expected body weight for their age,
• Engaged in binge eating at least once a week for 9 out of the 12 weeks prior to the study entry, and
• Were judged by a clinician to be stable enough to be treated for their psychiatric condition as an outpatient (i.e, no acute suicidality, hallucination, unstable vital signs or persistently abnormal laboratory results due to eating disorder).

You may not qualify if:

• Subjects whose psychotropic medications had been changed within 4 weeks prior to the entry or who had started psychotherapy within 3 months prior to the entry were excluded.
• Subjects were also excluded if they were taking carbonic anhydrase inhibitors, carbamazepine, phenytoin, phenobarbital, valproic acid, evening primrose oil or oral contraceptives.

Sponsors & Collaborators

• The Zucker Hillside Hospital: lead

Study Sites (1)

The Zucker Hillside Hospital

Glen Oaks, New York, 11004, United States

Location

MeSH Terms

Conditions

Feeding and Eating Disorders; Bulimia Nervosa; Binge-Eating Disorder

Interventions

Topiramate

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders

Intervention Hierarchy (Ancestors)

Fructose; Hexoses; Monosaccharides; Sugars; Carbohydrates; Ketoses

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: October 7, 2008
• First Posted: October 8, 2008
• Study Start: July 1, 2003
• Last Updated: October 8, 2008

Record last verified: 2008-09

Locations

US (1)