NCT01470508

Brief Summary

Promoviendo Alimentacion Saludable (PAS)"Promoting Healthy Eating" is a research project funded by the National Institute of Mental Health. The purpose of this study is to develop and test a treatment for eating disorders in Latina adults that is appropriate for their age and includes culturally appropriate family intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2010

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2010

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

November 9, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 11, 2011

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
Last Updated

May 18, 2016

Status Verified

May 1, 2016

Enrollment Period

5.6 years

First QC Date

November 9, 2011

Last Update Submit

May 16, 2016

Conditions

Keywords

BulimiaBinge-Eating DisorderEating Disorders

Outcome Measures

Primary Outcomes (1)

  • Change from Baseline in Eating Disorder Examination (EDE) Scores at End of Treatment

    End of Treatment will be measured by the completion of the twenty-five (25) scheduled therapy session, regardless of treatment group.

    Baseline, End of Treatment

Secondary Outcomes (18)

  • Change from Baseline in Beck Depression Inventory-Revised (BDI-R) score at Week 6 of Treatment

    Baseline, Week 6

  • Change from Baseline in Beck Depression Inventory-Revised (BDI-R) score at End of Treatment

    Baseline, End of Treatment

  • Change from Baseline in Beck Depression Inventory-Revised (BDI-R) score at 3 Month Follow-up

    Baseline, 3 Month Follow-up

  • Change from Baseline in the Symptom Checklist-36 (SCL-36) score at Week 6 of Treatment

    Baseline, Week 6 of Treatment

  • Change from Baseline in Symptom Checklist-36 (SCL-36) score at End of Treatment

    Baseline, End of Treatment

  • +13 more secondary outcomes

Other Outcomes (1)

  • M-FED Questionnaire

    3 Month Follow-up

Study Arms (2)

Family Enhancement

EXPERIMENTAL

PAS is a 27-week program consisting of 25 sessions, 50 minutes in length, between an individual and a therapist. During six (6) family sessions, a family member will accompany the individual to therapy and will take an active role during the session. In this program, individuals and their family members will learn about ways to communicate about their relationship in the context of experiencing an eating disorder. PAS focuses on family-specific skills such as communication skills and problem solving skills while also incorporating eating disorders psychoeducation.

Behavioral: Cognitive Behavioral Therapy with Family Enhancement

Cognitive Behavioral Therapy

ACTIVE COMPARATOR

Individuals meet their therapist once a week for 25 sessions, 50 minutes in length, for a period of 27 weeks for therapy.

Behavioral: Cognitive Behavioral Therapy

Interventions

Individuals meet with a therapist once a week for 25 sessions, 50 minutes in length, for a period of 27 weeks for therapy. Cognitive Behavioral Therapy is manualized and is the standard form of care at the UNC Eating Disorders Program.

Also known as: Eating disorder treatment as usual
Cognitive Behavioral Therapy

Individuals will meet with a therapist once a week for 25 sessions, 50 minutes in length, for a period of 27 weeks for therapy. Cognitive Behavioral Therapy with Family Enhancement is manualized and will involve the participation of family members during six (6) weeks of treatment.

Also known as: PAS
Family Enhancement

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • DSM-IV criteria for BN, BED, EDNOS (sub-threshold BN)
  • Latina
  • If taking antidepressant medication, stable dose for at least 3 months prior
  • Willingness to ask a family member or significant other to participate AND agreement of family member to participate

You may not qualify if:

  • Any major medical condition that would interfere with treatment or require alternative treatment
  • Alcohol or drug dependence in the last three months
  • Current significant suicidal ideation
  • Developmental disability that would impair the ability of the participant to benefit from psychotherapy effectively
  • Psychosis, including schizophrenia, or bipolar I disorder
  • Pregnancy
  • Body mass index below 17.5 kg/m\^2
  • If taking antidepressant medication, doses are not stable; individuals taking any medications that can significantly affect appetite or weight.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University of North Carolina

Chapel Hill, North Carolina, 27599-7160, United States

Location

UNC Center of Excellence for Eating Disorders

Chapel Hill, North Carolina, 27599, United States

Location

MeSH Terms

Conditions

Bulimia NervosaBinge-Eating DisorderBulimiaFeeding and Eating Disorders

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Mental DisordersHyperphagiaSigns and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Behavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Mae Lynn Reyes-Rodriguez, PhD

    University of North Carolina, Chapel Hill

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Clinical Assistant Professor in Psychiatry

Study Record Dates

First Submitted

November 9, 2011

First Posted

November 11, 2011

Study Start

August 1, 2010

Primary Completion

March 1, 2016

Study Completion

March 1, 2016

Last Updated

May 18, 2016

Record last verified: 2016-05

Locations