NCT02496507

Brief Summary

The purpose of this study is to investigate whether a device that allows office workers to sit or stand whilst working can reduce their sitting time at work and improve their health over 8 weeks.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
47

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2013

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2013

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2013

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

July 8, 2015

Completed
6 days until next milestone

First Posted

Study publicly available on registry

July 14, 2015

Completed
Last Updated

July 14, 2015

Status Verified

July 1, 2015

Enrollment Period

4 months

First QC Date

July 8, 2015

Last Update Submit

July 13, 2015

Conditions

Keywords

sittinginterventiondesksworkplacecardiovascularmetabolicqualitativerandomised controlled trial

Outcome Measures

Primary Outcomes (1)

  • Change from baseline in workplace sitting time at 4 and 8 weeks

    An ecological momentary assessment (EMA) diary assessed time spent sitting, standing, walking and in other activities during work hours over 5 days (Monday-Friday). At 15-minute intervals participants used a diary to record their main behaviour in response to the question: "What are you doing right now?" The options were sitting, standing, walking or other. If other was selected, participants were instructed to write the activity they were doing. Time spent in each behaviour per day was estimated by multiplying the frequency of recordings by 15. A diary day was considered valid if data entries were provided for ≥75% of time spent at work. Time spent in each behaviour was calculated for each valid day and means were calculated from valid days. To be retained for analyses, participants had to provide ≥2 valid days at each time point.

    Baseline (week 0), Mid-intervention (4 weeks), End-intervention (8 weeks)

Secondary Outcomes (15)

  • Change from baseline in workplace standing time at 4 and 8 weeks

    Baseline (week 0), Mid-intervention (4 weeks), End-intervention (8 weeks)

  • Change from baseline in workplace walking time at 4 and 8 weeks

    Baseline (week 0), Mid-intervention (4 weeks), End-intervention (8 weeks)

  • Change from baseline in flow-mediated dilation (FMD) at 8 weeks

    Baseline (week 0), End-intervention (8 weeks)

  • Change from baseline in carotid artery intima media thickness (cIMT) at 8 weeks

    Baseline (week 0), End-intervention (8 weeks)

  • Change from baseline in plasma glucose at 8 weeks

    Baseline (week 0), End-intervention (8 weeks)

  • +10 more secondary outcomes

Study Arms (2)

Intervention

EXPERIMENTAL

Provision of a sit-stand workstation for use at work.

Other: Sit-stand workstation

Control

NO INTERVENTION

Participants were asked to maintain their normal work practices and received no intervention. Participants were offered the opportunity to have a sit-stand workstation installed for 8 weeks after all data collection.

Interventions

After baseline, each participant had a sit-stand workstation installed on their existing workplace desk. A single or dual monitor WorkFit-A with Worksurface+ workstation was installed, dependent on the number of monitors. The monitor(s) and keyboard were housed on the workstation and the workstation could be quickly raised up and down by hand to enable seated or standing work. Participants were not prescribed an amount of time to use the station. Ergotron Ltd provided and installed the workstations and gave participants basic face-to-face training and ergonomic information on correct use. Participants received a web link to manufacturer ergonomic guidelines via an email from the research team. After end-intervention data collection, manufacturer staff uninstalled the workstations.

Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • full-time member of staff
  • access to a work telephone and desktop computer with internet

You may not qualify if:

  • have a cardiovascular or metabolic disease
  • taking any medication
  • pregnant
  • planned absence \> 1 week during the trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Liverpool John Moores University

Liverpool, Merseyside, L3 2AT, United Kingdom

Location

Related Publications (3)

  • Batterham AM, Hopkins WG. Making meaningful inferences about magnitudes. Int J Sports Physiol Perform. 2006 Mar;1(1):50-7.

  • Hopkins WG, Marshall SW, Batterham AM, Hanin J. Progressive statistics for studies in sports medicine and exercise science. Med Sci Sports Exerc. 2009 Jan;41(1):3-13. doi: 10.1249/MSS.0b013e31818cb278.

  • E F Graves L, C Murphy R, Shepherd SO, Cabot J, Hopkins ND. Evaluation of sit-stand workstations in an office setting: a randomised controlled trial. BMC Public Health. 2015 Nov 19;15:1145. doi: 10.1186/s12889-015-2469-8.

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Lee EF Graves, PhD

    Liverpool John Moores University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer/Senior Lecturer

Study Record Dates

First Submitted

July 8, 2015

First Posted

July 14, 2015

Study Start

August 1, 2013

Primary Completion

December 1, 2013

Study Completion

December 1, 2013

Last Updated

July 14, 2015

Record last verified: 2015-07

Locations