Study of Chronic Degenerative Diseases

NCT02495961 | Completed

• 1 other identifier: 2014-01
• Study Type: observational
• Target: 57
• Locations: 1 country
• Sites: 1

Brief Summary

The prevalence of obesity and type 2 diabetes mellitus (DM) in children have been increasing in parallel at an alarming rate. In particular, the increasing prevalence of type 2 DM is attributable to genetic factors, clinical (waist circumference, adiposity and physical condition) and biochemical (insulin secretion and sensitivity, lipids and inflammation) risk, each of which represents an independent risk. As has already studied and published in the investigators' group, the child population of Toluca has greater expression of cardiovascular risk factors than their counterparts in Bogota, Colombia. The metabolic characterization of the young population of Toluca and Bogota with new biomarkers such as homocysteine and leptin is an activity that aims to provide more metabolic data affecting young people. Hypothesis: After six months of follow-up there will be a greater relative risk in Mexican population to have identified another component of metabolic syndrome compared to the young population of Colombia.

Conditions

Metabolic Syndrome X

Keywords

hyperlipidemias; hyperglycemia; hypertension; leptin; hyperhomocysteinemia

Outcome Measures

Primary Outcomes (1)

• Metabolic syndrome component detection

  After six months of a basal evaluation, children will be re-examined in each component of the metabolic syndrome. Metabolic syndrome component detection will be determined by the measure of glucose (mg/dl), cholesterol (mg/dl), triglycerides (mg/dl), high-density lipoproteins (HDL), waist circumference (cm), hip circumference (cm) and blood pressure (mmHg).

  six months

Study Arms (2)

Low risk population

Colombian children, between 6 and 12 years old, regular students of a Primary school.

High risk population

Mexican children, between 6 and 12 years old, regular students of a Primary school.

Eligibility Criteria

• Age: 6 Years - 12 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Primary school students.

You may qualify if:

• Primary school students of medium-low income.

You may not qualify if:

• Children with disabilities or a known chronic disease.

Sponsors & Collaborators

• Asociación Científica Latina A.C.: lead
• Universidad Autonoma del Estado de Mexico: collaborator
• Ciprés Grupo Médico CGM SC: collaborator

Study Sites (1)

Asociación Científica Latina A.C.

Toluca, State of Mexico, 50120, Mexico

Location

MeSH Terms

Conditions

Metabolic Syndrome; Hyperlipidemias; Hyperglycemia; Hypertension; Hyperhomocysteinemia

Condition Hierarchy (Ancestors)

Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Dyslipidemias; Lipid Metabolism Disorders; Vascular Diseases; Cardiovascular Diseases; Amino Acid Metabolism, Inborn Errors; Metabolism, Inborn Errors; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Malabsorption Syndromes; Vitamin B Deficiency; Avitaminosis; Deficiency Diseases; Malnutrition; Nutrition Disorders

Study Officials

• Hugo Mendieta Zerón, PhD.

  Asociación Científica Latina A.C.

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 9, 2015
• First Posted: July 13, 2015
• Study Start: June 1, 2015
• Primary Completion: January 1, 2016
• Study Completion: February 1, 2016
• Last Updated: February 17, 2016

Record last verified: 2016-02

Locations

ME (1)