Examining Cortisol and Alpha Amylase in a Healthy Sample of Youth and Adults

NCT02490280 | Completed DMC

• 2 other identifiers: NA000833661K24MH096760-01A1
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to investigate how healthy youth and adults' cortisol levels and other hormone levels relate to anxiety levels while they participate in a behavioral task called the Trier Social Stress Task. Data from these healthy participants will also be compared to those of anxious youth and adults collected as part of the in the Principal Investigator's ongoing study titled, "Child/Adolescent Anxiety Multimodal Extended Long-term Study (NA00035687)."

Conditions

Anxiety

Outcome Measures

Primary Outcomes (1)

• Anxiety Disorders Interview Schedule for Diagnostic and Statistical Manual for Psychological Disorders-IV, Child and Parent Versions (C/P-ADIS), and Adult Versions (Client-ADIS)

  The C/P and Client-ADIS' are semi-structured diagnostic interviews used to assess symptoms of anxiety, depression, and behavioral issues. This interview will be administered by a trained staff member and will utilize information from both parents and children (if child is under 18 years of age) or from the adult participant (if the participant is 18 years of age or older). This interview will be used to determine the presence or absence of an anxiety disorder for participants in this study. The ADIS is administered one time because each participant only completes a single study visit.

  1 day

Study Arms (1)

Trier Social Stress Test

EXPERIMENTAL

Participants will be administered the Trier Social Stress Test (TSST). The TSST is the gold standard social stress test and involves speaking in front of confederate judges and completing arithmetic tasks. The task takes 10-15 minutes.

Behavioral: Trier Social Stress Test

Interventions

Trier Social Stress Test BEHAVIORAL

The TSST is the gold standard social stress test and involves speaking in front of confederate judges and completing arithmetic tasks. The task takes 10-15 minutes.

Trier Social Stress Test

Eligibility Criteria

• Age: 11 Years - 34 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Participant has no current psychiatric disorder
• Participant has no past psychiatric disorder
• Participant has no major medical disorder
• Participant is not currently receiving psychological or psychopharmacological treatment (medication) for any psychological disorder
• Participant is between the ages 11 and 34

You may not qualify if:

• Participant has or has had psychiatric disorder or medical condition contraindicating study participation
• Participant is pregnant
• Participant is not an English speaker
• Participant has a visual, motor, or hearing problem that would affect participation

Sponsors & Collaborators

• Johns Hopkins University: lead
• National Institute of Mental Health (NIMH): collaborator

Study Sites (1)

Johns Hopkins School of Medicine

Baltimore, Maryland, 21287, United States

Location

MeSH Terms

Conditions

Anxiety Disorders

Interventions

Psychological Tests

Condition Hierarchy (Ancestors)

Mental Disorders

Intervention Hierarchy (Ancestors)

Behavioral Disciplines and Activities

Study Officials

• Golda S Ginsburg, Ph.D.

  Johns Hopkins University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Adjunct Professor

Study Record Dates

• First Submitted: July 1, 2015
• First Posted: July 3, 2015
• Study Start: April 1, 2013
• Primary Completion: April 1, 2015
• Study Completion: April 1, 2015
• Last Updated: July 3, 2015

Record last verified: 2015-07

Locations

US (1)