NCT02484235

Brief Summary

Obesity is a global health problem since it is associated with many cardiovascular and metabolic diseases, osteoarticular problems and some cancers. That is why it is a priority of the national health policies. Exercise is a mainstay in the treatment, but still the most effective method is sought. The resistance exercise and high intensity intervals (HIIT) have been shown to positively affect the outcome of the disease, increasing the oxidative capacity of the trained subjects. Therefore it is important to look if both together produce greater benefits or otherwise nullify its effects, such as suggested by recent publications in relation to the cellular response to different stimuli such exercise in skeletal muscle. The aim of this study is to evaluate the effectiveness of interventions exercise high intensity intervals, overload and combining them in the oxidative capacity of obese subjects.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable obesity

Timeline
Completed

Started Jun 2015

Shorter than P25 for not_applicable obesity

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2015

Completed
22 days until next milestone

First Submitted

Initial submission to the registry

June 23, 2015

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 29, 2015

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
Last Updated

June 29, 2015

Status Verified

June 1, 2015

Enrollment Period

6 months

First QC Date

June 23, 2015

Last Update Submit

June 25, 2015

Conditions

Keywords

obesityexerciseHIITVo2kinetics

Outcome Measures

Primary Outcomes (1)

  • Exercise Test of Vo2 kinetics

    6 weeks

Secondary Outcomes (2)

  • Strength test of 10 maximum repetition (10RM)

    6 weeks

  • Exercise test of max Walking Speed

    6 weeks

Study Arms (3)

Group HIIT

EXPERIMENTAL

Only Aerobic Training with HIIT

Other: HIIT

Group Strength

EXPERIMENTAL

Only Strength Training

Other: Strength

HIIT and Strength

EXPERIMENTAL

Both intervention HIIT and Strength training

Other: HIITOther: Strength

Interventions

HIITOTHER

Group training with HIIT 3 times per week during 10 sessions

Group HIITHIIT and Strength

Group training with strength exercises 3 times per week during 10 sessions

Group StrengthHIIT and Strength

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Indication of medical supervised exercise
  • BMI of 25-35kg/m2
  • Participate in a 10 session rehabilitation program

You may not qualify if:

  • Osteomuscular injuries
  • Cardiovascular disease without control
  • Bariatric Surgery
  • High blood pressure without control

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Clinico de la Universidad de Chile

Santiago, Santiago Metropolitan, Chile

RECRUITING

MeSH Terms

Conditions

ObesityMotor Activity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBehavior

Central Study Contacts

Marcelo Cano, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
CARE PROVIDER, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PT

Study Record Dates

First Submitted

June 23, 2015

First Posted

June 29, 2015

Study Start

June 1, 2015

Primary Completion

December 1, 2015

Study Completion

March 1, 2016

Last Updated

June 29, 2015

Record last verified: 2015-06

Locations