Study of Effects of Light on the Vigilance and Cognitive Performance Following a Night Without Sleep

NCT02478528 | Completed

• 1 other identifier: 6191
• Study Type: interventional
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

Sleep disorders are a major public health issue, affecting 1 in 6 French. The medical impact at the individual level but also social and economic level (loss of productivity, morbidity, mortality) emphasize the need for one hand, to improve the investigators' understanding of these disorders in order to develop appropriate therapeutic tools and on the other hand, to increase the investigators' support abilities of patients with these disorders. The investigators' team of unity sleep from Strasbourg University Hospitals, in collaboration with the UPR 3212 CNRS team, is working on the development and adjustment of new concepts and tools to compensate the investigators' sleep debt in order to apply them to patients with sleep disorders and persons who face with sleep restriction.

Conditions

Healthy Volunteers

Outcome Measures

Primary Outcomes (2)

• Analysis of the perception of fatigue

  Karolinska Sleepiness Scale 3 sessions :

  Compare during the 3 sessions : energy-light lamp, luminettes lamp and control condition

• Analysis of the circadian variation of melatonin and cortisol secretion

  cortisol and melatonin dosage

  Compare during the 3 sessions : energy-light lamp, luminettes lamp and control condition

Secondary Outcomes (1)

• Cognitive performance

  Compare during the 3 sessions : energy-light lamp, luminettes lamp and control condition

Study Arms (1)

Experimental

EXPERIMENTAL

Device: Energy-Light lamp; Device: Luminettes lamp; Other: control condition

Interventions

Energy-Light lamp DEVICE

Exposure of the subject, at 5am, to the light source of Energy-Light lamp (Philips)

Experimental

Luminettes lamp DEVICE

Exposure of the subject, at 5am, to the light source of Luminettes lamp (Lucimed)

Experimental

control condition OTHER

No exposure of the subject to any light sources (control condition)

Experimental

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Man or woman
• Age from 18 to 40 years
• With a Body Mass Index (BMI) between 17 and 30 kg m-2
• Healthy volunteer determined by clinical examination and psychological interview
• Agreeing to abstain from caffeine, nicotine, alcohol, psychotropic drugs, cannabis or other drugs, the week before the start of Stage 2 of the study until the end of the study
• Dated and signed informed consent
• Subjet affiliated to a social security scheme
• Subject has been informed about the results of the medical examination

You may not qualify if:

• Cons-indications to the use of the medical device
• Ocular disease
• Unable to give informations to the subject (subject in an emergency situation, difficulties in understanding, ...)
• Subjet under judicial protection
• Subject under guardianship or curatorship
• pregnancy
• breastfeeding

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Unité du Sommeil - Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France

Location

Related Publications (1)

• Comtet H, Geoffroy PA, Kobayashi Frisk M, Hubbard J, Robin-Choteau L, Calvel L, Hugueny L, Viola AU, Bourgin P. Light therapy with boxes or glasses to counteract effects of acute sleep deprivation. Sci Rep. 2019 Dec 2;9(1):18073. doi: 10.1038/s41598-019-54311-x.

  PMID: 31792259 RESULT

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 26, 2015
• First Posted: June 23, 2015
• Study Start: May 1, 2015
• Primary Completion: June 1, 2015
• Study Completion: June 1, 2015
• Last Updated: December 22, 2025

Record last verified: 2025-12

Locations

FR (1)