NCT02475512

Brief Summary

Incontinence is a widespread problem in all health care setting. One of the main complications of incontinence is inflammation of the skin in the genital and anal region, also known as incontinence-associated dermatitis (IAD). IAD is a known risk factor of pressure ulcer development. Prevalence figures of IAD vary between 5.6% and 50%. The primary aim of this study is to compare the effectiveness of a 3-in-1 genital wipe versus standard care (traditional water and soap) for the prevention of IAD. The second aim is to perform a health economic evaluation of the 3-in-1 genital wipe versus standard care, and third to compare the cost of a 2-in-1 total body wash wipe versus standard care for total body wash. Other outcomes are the comfort and tolerance of both the nurses and participants. In this Randomized Controlled Trial, performed in 13 long-term care settings, the participants will undergo a 30 day study period. In the experimental intervention, the participants will be washed with body wash wipes and genital wipes. In the control group, the subjects will receive traditional care. IAD as well as Pressure Ulcer prevalence will be monitored. Subjective and objective time measurements will be performed.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
385

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

11 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2015

Completed
20 days until next milestone

First Submitted

Initial submission to the registry

May 21, 2015

Completed
28 days until next milestone

First Posted

Study publicly available on registry

June 18, 2015

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

February 9, 2016

Status Verified

February 1, 2016

Enrollment Period

7 months

First QC Date

May 21, 2015

Last Update Submit

February 8, 2016

Conditions

Keywords

elderlylong-term care

Outcome Measures

Primary Outcomes (1)

  • Incidence and category of Incontinence-Associated Dermatitis

    within the first 30 days after start of the study

Secondary Outcomes (5)

  • Incidence and category of Pressure Ulcers

    within the first 30 days after start of the study

  • Comfort and tolerance of the participant

    On baseline, at day 14 and at day 30 (the end of the study)

  • Comfort and preferences of the caregiver

    On baseline, at day 14 and at day 30 (the end of the study)

  • adverse effects of the intervention

    within the first 30 days after start of the study

  • Cost of the experiment (use of wash wipes) versus the standard care

    For the duration of the study (30 days)

Study Arms (2)

Wash wipes

EXPERIMENTAL

Washing with water and soap (standard care) will be replaced with two wash wipes during 30 days: (1) daily total body wash (using 3M Cavilon Bathing and Cleansing wipes) and (2) Continence Care (using 3M Cavilon Continence Care Wipes). No other preventive barrier or hydration products will be allowed in the genital-anal region.

Other: Wash wipes (3M)

Standard care

PLACEBO COMPARATOR

Washing will be done using water and pH neutral soap. No other preventive barrier or hydration products will be allowed in the genital-anal region.

Other: water and pH neutral soap

Interventions

Also known as: 3M Cavilon Bathing & Cleansing Wipes, 3M Cavilon Continence Care Wipes
Wash wipes
Standard care

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • urinary incontinence, fecal incontinence or double incontinence
  • depending on help for washing
  • free of skin damage (without signs of pressure ulcers or IAD such as skin breakdown or redness)

You may not qualify if:

  • not incontinent or minor incontinent (e.g. stress incontinence)
  • urinary or fecal catheter
  • use of incontinence wipes in the uro-genital area two weeks prior to the start of the study
  • the use of a skin barrier product in the uro-genital area two weeks prior to screening
  • presence of a bacterial/fungal infection in the uro-genital area

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (11)

Woonzorgcentrum Sint-Jozef

Bruges, Belgium

Location

Woonzorgcentrum Ceder aan de Leie

Harelbeke, Belgium

Location

Woonzorgcentrum Heilig Hart

Kortrijk, Belgium

Location

Woonzorgcentrum Sint-Jozef

Kortrijk, Belgium

Location

Woonzorgcentrum De Samaritaan

Nukerke, 9681, Belgium

Location

Woonzorgcentrum de Boarebreker

Ostend, Belgium

Location

Woonzorgcentrum De Kroon

Sint-Gillis-Waas, Belgium

Location

Woonzorgcentrum Deken Darras

Tielt, Belgium

Location

Woonzorgcentrum Onze Lieve Vrouw van Lourdes

Wakken, Belgium

Location

Woonzorgcentrum Duneroze

Wenduine, Belgium

Location

Woonzorgcentrum Sint-Camillus

Wevelgem, Belgium

Location

Related Publications (1)

  • Beeckman D, Van Lancker A, Van Hecke A, Verhaeghe S. A systematic review and meta-analysis of incontinence-associated dermatitis, incontinence, and moisture as risk factors for pressure ulcer development. Res Nurs Health. 2014 Jun;37(3):204-18. doi: 10.1002/nur.21593. Epub 2014 Apr 3.

    PMID: 24700170BACKGROUND

Related Links

MeSH Terms

Conditions

Diaper RashPressure Ulcer

Interventions

Water

Condition Hierarchy (Ancestors)

Dermatitis, IrritantDermatitis, ContactDermatitisSkin DiseasesSkin and Connective Tissue DiseasesSkin Diseases, EczematousSkin Ulcer

Intervention Hierarchy (Ancestors)

HydroxidesAlkaliesInorganic ChemicalsAnionsIonsElectrolytesOxidesOxygen Compounds

Study Officials

  • Dimitri Beeckman, PhD

    University Ghent

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
University Centre for Nursing and midwifery

Study Record Dates

First Submitted

May 21, 2015

First Posted

June 18, 2015

Study Start

May 1, 2015

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

February 9, 2016

Record last verified: 2016-02

Locations