NCT02436382

Brief Summary

Neonatal hypothermia is associated with increased risk of mortality as well as multiple morbidities. The investigators objective is to determine if an increase in ambient operative room temperature decreases the rate of hypothermia. Operating room temperature will be randomized to the current institutional standard (67°F) or a temperature of 73°F on a weekly basis for a period of six months.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
846

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 30, 2015

Completed
2 days until next milestone

Study Start

First participant enrolled

February 1, 2015

Completed
3 months until next milestone

First Posted

Study publicly available on registry

May 6, 2015

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2015

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2015

Completed
Last Updated

May 11, 2016

Status Verified

May 1, 2016

Enrollment Period

6 months

First QC Date

January 30, 2015

Last Update Submit

May 10, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • neonatal hypothermia

    a core temperature of less than 36.5C

    up to 2 hours following delivery

Secondary Outcomes (1)

  • maternal hypothermia

    up to 10 hours following delivery

Other Outcomes (1)

  • neonatal hypoglycemia

    up to 8 hours following delivery

Study Arms (2)

Ambient Temperature of 67F

NO INTERVENTION

These patients will have an operating room temperature of 67F for cesarean delivery, the standard of care at our institution.

Ambient Temperature of 73F

ACTIVE COMPARATOR

These patient will have an operating room temperature of 73F for cesarean delivery, a temperature more consistent with WHO recommendations.

Other: change in temperature

Interventions

increase in ambient room temperature

Ambient Temperature of 73F

Eligibility Criteria

Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • All pregnant women and their neonates undergoing cesarean delivery by the Parkland Hospital Obstetrics Service on the Labor and Delivery "West" Unit (operating rooms 1, 2, 3, and 5) during the study period.

You may not qualify if:

  • Subjects will be excluded from the study if cesarean delivery is planned but a precipitous vaginal delivery occurs, intrauterine fetal demise has been diagnosed prior to start of surgery, the neonate is noted to have a major congenital anomaly, resuscitative efforts are not performed ("comfort care only" provided), or a neonatal temperature is not available.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Parkland Memorial Hospital

Dallas, Texas, 75235, United States

Location

MeSH Terms

Conditions

Hypothermia

Interventions

Temperature

Condition Hierarchy (Ancestors)

Body Temperature ChangesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

ThermodynamicsPhysical PhenomenaWeatherAtmosphereEnvironmentEcological and Environmental PhenomenaBiological PhenomenaMeteorological ConceptsEnvironment, ControlledEnvironment and Public Health

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Fellow Physician

Study Record Dates

First Submitted

January 30, 2015

First Posted

May 6, 2015

Study Start

February 1, 2015

Primary Completion

August 1, 2015

Study Completion

September 1, 2015

Last Updated

May 11, 2016

Record last verified: 2016-05

Locations