NCT00904228

Brief Summary

The purpose of this research project is to ascertain the effectiveness of plastic head covering in prevention of hypothermia. Hypothermia is defined by body temperature \<36.5º Celsius by the World Health Organization. The surface area of the head is about 20% of total body surface of a newborn infant and is a major source of heat loss. The objective is to compare rectal temperature upon admission to the neonatal intensive care between preterm neonates who had stockinet head covering and those who had plastic-lined stockinet head covering placed in the delivery room. The investigators aim to demonstrate that plastic-lined head covering is more effective than stockinet head covering alone in maintaining body temperature.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
260

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2008

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2008

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

February 27, 2009

Completed
3 months until next milestone

First Posted

Study publicly available on registry

May 19, 2009

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2010

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2010

Completed
Last Updated

April 25, 2019

Status Verified

April 1, 2019

Enrollment Period

2 years

First QC Date

February 27, 2009

Last Update Submit

April 23, 2019

Conditions

Keywords

hypothermiaeuthermiahyperthermiamortalitymorbiditysepsisbronchopulmonary dysplasiaintraventricular hemorrhageventilator days

Outcome Measures

Primary Outcomes (1)

  • Hypothermia

    admission rectal temperature \<36.5C

    1 hour

Secondary Outcomes (7)

  • Mortality

    1 year

  • Infection

    1 year

  • Necrotizing enterocolitis

    1 year

  • Intraventricular Hemorrhage

    1 year

  • Bronchopulmonary Dysplasia

    1 year

  • +2 more secondary outcomes

Study Arms (2)

Plastic Cap

EXPERIMENTAL

Plastic lined stockinet cap (polyethylene bag)

Other: placement of plastic cap during delivery room stabilization

Stockinet Cap

ACTIVE COMPARATOR

Usual practice

Other: placement of routine cap during delivery room stabilization

Interventions

placement of plastic cap during delivery room stabilization

Plastic Cap

Eligibility Criteria

AgeUp to 1 Hour
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Infants with less than 33 week gestational age by obstetrical dating
  • Infants delivered in Parkland Memorial Hospital Labor and Delivery areas
  • Infant whose delivery was attended by the Parkland Neonatal Resuscitation Team
  • Infant whos is viable

You may not qualify if:

  • Infant who has 33 week gestational age or greater by obstetrical dating
  • Infant who is deemed non-viable
  • Infant who did not have the Parkland Neonatal Resuscitation Team present at time of birth
  • Infant with congenital anomaly which precludes measurement of rectal temperature (such as anal atresia or imperforate anus)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Parkland Memorial Hospital

Dallas, Texas, 75390, United States

Location

MeSH Terms

Conditions

HypothermiaHyperthermiaSepsisBronchopulmonary Dysplasia

Condition Hierarchy (Ancestors)

Body Temperature ChangesSigns and SymptomsPathological Conditions, Signs and SymptomsHeat Stress DisordersWounds and InjuriesInfectionsSystemic Inflammatory Response SyndromeInflammationPathologic ProcessesVentilator-Induced Lung InjuryLung InjuryLung DiseasesRespiratory Tract DiseasesInfant, Premature, DiseasesInfant, Newborn, DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • Lilian T StJohn, MD

    University of Texas Southwestern Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Pediatrics

Study Record Dates

First Submitted

February 27, 2009

First Posted

May 19, 2009

Study Start

September 1, 2008

Primary Completion

September 1, 2010

Study Completion

December 1, 2010

Last Updated

April 25, 2019

Record last verified: 2019-04

Locations