NCT02417493

Brief Summary

The purpose of the present study is to determine if asking adolescent patients (ages 13-17) to self-inject an empty syringe into their thigh during routine clinic visits results in increased reported comfort with self-injection, reduced anxiety regarding self-injection and food allergy management for both patient and caregiver(s), and in greater perceived likelihood of epinephrine self-injection, in the event of an emergency.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2015

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

April 10, 2015

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 15, 2015

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2016

Completed
Last Updated

July 1, 2016

Status Verified

June 1, 2016

Enrollment Period

1.3 years

First QC Date

April 10, 2015

Last Update Submit

June 30, 2016

Conditions

Keywords

Food allergyself-managementepinephrine self-injectionnterventionadolescents

Outcome Measures

Primary Outcomes (1)

  • Child comfort with epinephrine self-injection

    Immediate pre-post differences within the intervention group in the score obtained on a child-reported "comfort with self-injection" questionnaire.

    Day 1

Secondary Outcomes (4)

  • Child likelihood of epinephrine self-injection

    Day 1

  • Parent report of child comfort with epinephrine self-injection

    Day 1

  • Child comfort with epinephrine self-injection

    1 month post-intervention

  • Parent report of child comfort with epinephrine self-injection

    1 month post-intervention

Study Arms (2)

Simulation of Epinephrine Self-Injection

EXPERIMENTAL

The patient will self-inject an empty syringe into his/her thigh simulating a self-injection of epinephrine during a routine outpatient visit to the allergist.

Behavioral: Simulation of epinephrine self-injection

Control Group

NO INTERVENTION

The patient will be encouraged to speak to their physician about self-injection, but will not undergo the self-injection protocol during a routine outpatient visit to the allergist.

Interventions

Simulation of Epinephrine Self-Injection

Eligibility Criteria

Age13 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Patients seen in the outpatient clinic and their caretakers (no inpatients).
  • Patients must have been diagnosed with food allergy and previously prescribed self-injectable epinephrine.
  • Patients between the ages of 13-17 years old.
  • Parent consent and child assent.

You may not qualify if:

  • Patients and caregiver(s) who have been diagnosed with cognitive barriers that prevent them from understanding the study, as determined by either: a previously diagnosed mental retardation or inability to repeat the study protocol at the time of consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jaffe Food Allergy Institute

New York, New York, 10029, United States

Location

MeSH Terms

Conditions

Food Hypersensitivity

Condition Hierarchy (Ancestors)

Hypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • Eyal Shemesh, MD

    Icahn School of Medicine at Mount Sinai

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 10, 2015

First Posted

April 15, 2015

Study Start

March 1, 2015

Primary Completion

June 1, 2016

Study Completion

June 1, 2016

Last Updated

July 1, 2016

Record last verified: 2016-06

Locations