Factors Associated With Maintenance of Antibody Responses to Influenza Vaccine in Older, Community-Dwelling Adults
1 other identifier
observational
510
0 countries
N/A
Brief Summary
Little is known about factors associated with maintenance of hemagglutinin inhibition (HAI) antibodies after influenza vaccination in older adults so the investigators enrolled adults ≥50 years.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2009
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2014
CompletedFirst Submitted
Initial submission to the registry
March 9, 2015
CompletedFirst Posted
Study publicly available on registry
March 30, 2015
CompletedMarch 30, 2015
March 1, 2015
10 months
March 9, 2015
March 27, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Maintenance of Immune Response using Hemagglutinin inhibition titers
1 year
Interventions
Everyone immunized as recommended by current guidelines
Eligibility Criteria
Subjects were enrolled at Vanderbilt University Medical Center and Marshfield Clinic Research Foundation during September and October 2009. Subjects were eligible for recruitment if they were ≥50 years of age and had no previous allergy or reaction to influenza vaccination.
You may qualify if:
- Age \>=50 years
You may not qualify if:
- Prior vaccine allergy or history of guillain barre
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Vanderbilt Universitylead
- Centers for Disease Control and Preventioncollaborator
- Marshfield Clinic Research Foundationcollaborator
Related Publications (1)
Talbot HK, Coleman LA, Zhu Y, Spencer S, Thompson M, Cheng PY, Sundaram ME, Belongia EA, Griffin MR. Factors associated with maintenance of antibody responses to influenza vaccine in older, community-dwelling adults. BMC Infect Dis. 2015 Apr 23;15:195. doi: 10.1186/s12879-015-0926-8.
PMID: 25903659DERIVED
Biospecimen
serum samples were collected
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
March 9, 2015
First Posted
March 30, 2015
Study Start
September 1, 2009
Primary Completion
July 1, 2010
Study Completion
January 1, 2014
Last Updated
March 30, 2015
Record last verified: 2015-03