NCT02391987

Brief Summary

This study evaluates the effectiveness of remote tele-monitoring and health coaching in helping to reduce hospitalizations in heart failure patients. Half of participants will receive tele-monitoring and health coaching, while the other half will receive standard health care provided by their chosen provider.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
112

participants targeted

Target at P50-P75 for not_applicable heart-failure

Timeline
Completed

Started May 2015

Typical duration for not_applicable heart-failure

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 12, 2015

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 18, 2015

Completed
1 month until next milestone

Study Start

First participant enrolled

May 1, 2015

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2019

Completed
11 months until next milestone

Results Posted

Study results publicly available

January 29, 2020

Completed
Last Updated

January 29, 2020

Status Verified

January 1, 2020

Enrollment Period

3.8 years

First QC Date

March 12, 2015

Results QC Date

January 16, 2020

Last Update Submit

January 16, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Hospital Readmission

    Occurrence of all-cause hospital readmissions or death within 60 days

    60 days

Secondary Outcomes (2)

  • Number of Readmissions or Visits

    60 days

  • Mortality

    60 days

Study Arms (2)

Tele-Monitoring

ACTIVE COMPARATOR

Tele-monitoring and health coaching in addition to standard health care

Device: Tele-monitoring and health coaching

Standard Care

NO INTERVENTION

Standard care is defined as Heart Failure (HF) care based on current American College of Cardiology (ACC) and American Heart Association (AHA) HF guidelines implemented and orchestrated by a cardiologist and support staff at the participating institution.

Interventions

Tele-monitoring involves a personal monitoring system used to analyze data to provide relevant health information back to the treating clinician and the user. The monitoring system remotely monitors electrocardiographic (ECG) signals, heart rate, breathing rate, and activity levels. Additional devices will be integrated with the monitoring device to assess blood pressure and weight. Health Coaching involves a team of health care professionals including a registered nurse (RN) . The health care team creates a plan specific to the patient and provides guidance on nutrition' medications, and exercise. The data collected by the remote monitoring device will assist the care team in patient management.

Tele-Monitoring

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Hospitalized with primary or secondary diagnosis of Acute Decompensated Heart Failure (one or more of these symptoms: shortness of breath, orthopnea or edema AND one or more of these signs: rales, peripheral edema, ascites, or pulmonary vascular congestion on chest radiography)
  • Adult patients \>18 years old

You may not qualify if:

  • Overall life expectancy \< 1 year
  • Known skin allergy to adhesives (hydrocolloid, silicone, acrylic)
  • Active systemic infection
  • Pregnant or lactating
  • End stage renal disease on dialysis
  • Subject or caregiver is not visually and tactile capable of smartphone and home device usage
  • Inadequate cell phone coverage (including international patients or international travel during study period)
  • Subject or legal guardian is not willing and able to provide appropriate informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Mayo Clinic

Jacksonville, Florida, 32224, United States

Location

Memorial Regional Medical Center

Mechanicsville, Virginia, 23116, United States

Location

St. Francis Medical Center

Midlothian, Virginia, 23114, United States

Location

St. Mary's Hospital

Richmond, Virginia, 23226, United States

Location

Mayo Clinic Health Systems

La Crosse, Wisconsin, 54601, United States

Location

Related Links

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Results Point of Contact

Title
Charles J. Bruce
Organization
Mayo Clinic

Study Officials

  • Charles Bruce, MD

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Medicine, College of Medicine

Study Record Dates

First Submitted

March 12, 2015

First Posted

March 18, 2015

Study Start

May 1, 2015

Primary Completion

March 1, 2019

Study Completion

March 1, 2019

Last Updated

January 29, 2020

Results First Posted

January 29, 2020

Record last verified: 2020-01

Locations