NCT02375373

Brief Summary

This prospective study will assess the effects of adding legumes, especially chick peas, to the diet of healthy adults on the commensal bacteria from feces of human subjects and resulting self-reported GI symptoms as well as markers of immune function.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2015

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 24, 2015

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 2, 2015

Completed
1 month until next milestone

Study Start

First participant enrolled

April 1, 2015

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
3 months until next milestone

Results Posted

Study results publicly available

February 19, 2016

Completed
Last Updated

February 19, 2016

Status Verified

January 1, 2016

Enrollment Period

8 months

First QC Date

February 24, 2015

Results QC Date

December 1, 2015

Last Update Submit

January 22, 2016

Conditions

Keywords

Gut Microbiota

Outcome Measures

Primary Outcomes (1)

  • Changes in Number of 16S RNA Sequences on Days 31, Day 62, and Day 93.

    Compare the gut microbiota composition of individual subjects before and after the implementation of a controlled and observed diet of chickpeas and legume products.

    Change from Day 31, Day 62, and Day 93

Study Arms (1)

Observational Chickpea Diet

Observed long-term to study legume intake and GI health (Observational Chickpea Diet)

Other: Observational Chickpea Diet

Interventions

Individuals encouraged to maintain increased legume intake and explore new recipes that allow them to maintain a diverse menu of legume based foods. Fecal samples collected monthly.

Also known as: Go'Bonzo's
Observational Chickpea Diet

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Individuals directly associated with the University of Florida (faculty, staff, students) or through the University of Florida's Health Street program.

You may qualify if:

  • Good Health
  • No systemic antibiotics during the preceding two months
  • No medication suppressing immune function
  • Willingness to provide basic demographic as well as medical history data

You may not qualify if:

  • Gastric Ulcers
  • Inflammatory Bowel Disease (IBD) or Irritable Bowel Syndrome (IBS)
  • Chronic constipation/diarrhea
  • Body Mass Index (BMI) \> 30
  • Dietary restrictions that prevent legume intake
  • Currently on any medication that can affect GI transit time
  • Consumption of \>3 servings/week of chickpeas or \>6 servings/week of legumes BEFORE study begins

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Emerging Pathogens Institiute

Gainesville, Florida, 32608, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

Fecal

MeSH Terms

Conditions

Inflammation

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Volker Mai, PhD, MPH
Organization
University of Florida

Study Officials

  • Volker Mai, PhD, MPH

    Associate Professor

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 24, 2015

First Posted

March 2, 2015

Study Start

April 1, 2015

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

February 19, 2016

Results First Posted

February 19, 2016

Record last verified: 2016-01

Locations