NCT02369497

Brief Summary

This is a prospective study on the Ascension HRA device to collect data to assess the safety and effectiveness of the HRA.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
59

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Dec 2007

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2007

Completed
6.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2014

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

November 4, 2014

Completed
4 months until next milestone

First Posted

Study publicly available on registry

February 24, 2015

Completed
Last Updated

February 24, 2015

Status Verified

February 1, 2015

Enrollment Period

6.6 years

First QC Date

November 4, 2014

Last Update Submit

February 17, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • American Shoulder and Elbow Surgeons (ASES) Score

    The American Shoulder and Elbow Score is a functional outcome tool that has been validated for various shoulder conditions

    2 years

Secondary Outcomes (4)

  • Range of Motion

    2 years

  • Visual Analog Scale for pain

    2 years

  • X-rays

    2 years

  • Adverse events

    Surgery; 3 month, 6 month, 1 year and 2 years post-op

Study Arms (1)

Primary cohort

Primary cohort of subjects who receive the HRA device.

Device: HRA

Interventions

HRADEVICE

Humeral head resurfacing with the HRA device

Primary cohort

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with arthritis requiring humeral resurfacing arthroplasty

You may qualify if:

  • The following patient will be included in the study - Patient who:
  • Is treated with the Ascension HRA
  • Is disabled by either non-inflammatory or inflammatory arthritis (i.e. rheumatoid arthritis, osteoarthritis and avascular necrosis
  • Has mild or moderate humeral head deformity and /or limited motion
  • Has post-traumatic arthritis
  • Has an intact or reparable rotator cuff
  • Has the means and ability to return for all required study visits
  • Is willing to participate in the study
  • Has signed an Informed Consent Form
  • Is at least 18 years of age and skeletally mature at the time of surgery
  • Is less than 75 years of age at the time of surgery

You may not qualify if:

  • Infection, sepsis, and osteomyelitis
  • Osteoporosis
  • Metabolic disorders which may impair bone formation
  • Osteomalacia
  • Rapid joint destruction, marked bone loss or bone resorption apparent on X-ray
  • Revision procedures where other devices or treatments have failed
  • Refuses to be in the study; or does not have the means and ability to return for all required study visits
  • Currently participating in another clinical study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bay Pines VA Healthcare System

Bay Pines, Florida, 33744, United States

Location

MeSH Terms

Conditions

Arthritis

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal Diseases

Study Officials

  • Candi Langmaid, MPH, CCRP

    Integra LifeSciences

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 4, 2014

First Posted

February 24, 2015

Study Start

December 1, 2007

Primary Completion

July 1, 2014

Study Completion

July 1, 2014

Last Updated

February 24, 2015

Record last verified: 2015-02

Locations