Effect of Transcranial Direct Current Stimulation (tDCS) on Appetite Control Related Brain Regions
1 other identifier
interventional
15
1 country
1
Brief Summary
The purpose of this study is to investigate the effect of Transcranial Direct Current Stimulation (tDCS) on appetite control related brain regions.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable obesity
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2015
CompletedFirst Submitted
Initial submission to the registry
February 2, 2015
CompletedFirst Posted
Study publicly available on registry
February 13, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2015
CompletedFebruary 4, 2016
February 1, 2016
8 months
February 2, 2015
February 3, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
Regional brain activity measured by blood-oxygen-level dependent (BOLD) signal of functional MRI
3T MR scanner with Echo Planar Imaging(EPI) capability(Magnetom, Siemens Medical System)
Immediately after intervention
Secondary Outcomes (1)
Behavior outcomes on the visual analog scale
Immediately after intervention
Study Arms (2)
Sham tDCS
EXPERIMENTALSubjects will receive tDCS two times, one is active stimulation and the other is sham stimulation. Both stimulations will be separated at least one week and the order of sham and active tDCS will be counterbalanced across subjects.
Real tDCS
EXPERIMENTALSubjects will receive tDCS two times, one is active stimulation and the other is sham stimulation. Both stimulations will be separated at least one week and the order of sham and active tDCS will be counterbalanced across subjects.
Interventions
For active tDCS, a 2 mA current will be delivered for 20 minutes with 20 second up and down ramp times. The anodal electrode will be placed on the right DLPFC (F4; 10-20 EEG system), and the cathode electrode will be placed on the left DLPFC (F4;10-20 EEG system), which is known to be related to cognitive function. The electrodes used for tDCS are saline-soaked sponges (25 cm2).
Eligibility Criteria
You may qualify if:
- BMI \> 28 kg/m2
You may not qualify if:
- history of brain trauma, epilepsy, or other neurological problems
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Chungbuk National University
Cheongju-si, North Chungcheong, 361-711, South Korea
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical Assistant Professor
Study Record Dates
First Submitted
February 2, 2015
First Posted
February 13, 2015
Study Start
February 1, 2015
Primary Completion
October 1, 2015
Last Updated
February 4, 2016
Record last verified: 2016-02